Endophytic fungi—alternative sources of cytotoxic compounds: a review

F Uzma, CD Mohan, A Hashem, NM Konappa… - Frontiers in …, 2018 - frontiersin.org
Cancer is a major cause of death worldwide, with an increasing number of cases being
reported annually. The elevated rate of mortality necessitates a global challenge to explore …

Fungal endophytes: Microfactories of novel bioactive compounds with therapeutic interventions; A comprehensive review on the biotechnological developments in the …

A Gupta, V Meshram, M Gupta, S Goyal, KA Qureshi… - Biomolecules, 2023 - mdpi.com
The seminal discovery of paclitaxel from endophytic fungus Taxomyces andreanae was a
milestone in recognizing the immense potential of endophytic fungi as prolific producers of …

Endophytic fungi with antitumor activities: Their occurrence and anticancer compounds

L Chen, QY Zhang, M Jia, QL Ming, W Yue… - Critical reviews in …, 2016 - Taylor & Francis
Plant endophytic fungi have been recognized as an important and novel resource of natural
bioactive products, especially in anticancer application. This review mainly deals with the …

The antitumor activity of naturally occurring chromones: A review

Y Jiang, F Guo, L Chen, L Xu, W Zhang, B Liu - Fitoterapia, 2019 - Elsevier
Chromones are a group of compounds widely distributed in nature with wide range of
biological activities, including antitumor, antimicrobial, antiviral, anti-inflammatory …

Redefining common endophytes and plant pathogens in Neofabraea, Pezicula, and related genera

C Chen, GJM Verkley, G Sun, JZ Groenewald… - Fungal Biology, 2016 - Elsevier
Abstract Species in Neofabraea, Pezicula, and related genera have been reported as
saprobes, plant pathogens or endophytes from a wide range of hosts. The asexual morphs …

Focused review on dual inhibition of quorum sensing and efflux pumps: a potential way to combat multi drug resistant Staphylococcus aureus infections

B Kaur, J Gupta, S Sharma, D Sharma… - International Journal of …, 2021 - Elsevier
Staphylococcus aureus is a common cause of skin infections, food poisoning and severe life-
threatening infections. Methicillin-Resistant Staphylococcus aureus (MRSA) is known to …

Bioprospecting of endophytic microorganisms for bioactive compounds of therapeutic importance

A Raimi, R Adeleke - Archives of Microbiology, 2021 - Springer
Presently, several drug discovery investigations on therapeutic management of human
health are aimed at bioprospecting for microorganisms, especially endophytic microbes of …

Metabolomics-guided isolation of anti-trypanosomal metabolites from the endophytic fungus Lasiodiplodia theobromae

N Kamal, CV Viegelmann, CJ Clements… - Planta …, 2017 - thieme-connect.com
Fungal endophytes offer diverse and unique secondary metabolites, making these
organisms potential sources of promising drug leads. The application of high-resolution …

Phialomustin A–D, new antimicrobial and cytotoxic metabolites from an endophytic fungus, Phialophora mustea

Y Nalli, DN Mirza, ZA Wani, B Wadhwa, FA Mallik… - RSC …, 2015 - pubs.rsc.org
Phialomustin A–D (1–4), four new bioactive metabolites, with an unprecedented azaphilone
derived skeleton, were isolated and characterized from an endophytic fungus isolated from …

Diapolic acid A–B from an endophytic fungus, Diaporthe terebinthifolii depicting antimicrobial and cytotoxic activity

N Yedukondalu, P Arora, B Wadhwa, FA Malik… - The Journal of …, 2017 - nature.com
Endophytes are diverse microbial communities including bacteria, fungi and actinomycetes
that live within the plant tissues, at least for a part of their life cycle, without causing any …