The global epidemic of SARS‐CoV‐2 variants and their mutational immune escape
D Tian, YH Sun, JM Zhou, Q Ye - Journal of medical virology, 2022 - Wiley Online Library
During the COVID‐19 pandemic, genetic variants of SARS‐CoV‐2 have been emerging and
spreading around the world. Several SARS‐CoV‐2 endemic variants were found in United …
spreading around the world. Several SARS‐CoV‐2 endemic variants were found in United …
Understanding the secret of SARS-CoV-2 variants of concern/interest and immune escape
F Lou, M Li, Z Pang, L Jiang, L Guan, L Tian… - Frontiers in …, 2021 - frontiersin.org
The global pandemic of the coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), places a heavy burden on global public …
respiratory syndrome coronavirus 2 (SARS-CoV-2), places a heavy burden on global public …
Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant
We identified an emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples …
variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples …
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation
Many enveloped viruses induce multinucleated cells (syncytia), reflective of membrane
fusion events caused by the same machinery that underlies viral entry. These syncytia are …
fusion events caused by the same machinery that underlies viral entry. These syncytia are …
Nucleocapsid mutations R203K/G204R increase the infectivity, fitness, and virulence of SARS-CoV-2
Previous work found that the co-occurring mutations R203K/G204R on the SARS-CoV-2
nucleocapsid (N) protein are increasing in frequency among emerging variants of concern …
nucleocapsid (N) protein are increasing in frequency among emerging variants of concern …
Changing composition of SARS-CoV-2 lineages and rise of Delta variant in England
Background Since its emergence in Autumn 2020, the SARS-CoV-2 Variant of Concern
(VOC) B. 1.1. 7 (WHO label Alpha) rapidly became the dominant lineage across much of …
(VOC) B. 1.1. 7 (WHO label Alpha) rapidly became the dominant lineage across much of …
[HTML][HTML] Mortality and critical care unit admission associated with the SARS-CoV-2 lineage B. 1.1. 7 in England: an observational cohort study
Background A more transmissible variant of SARS-CoV-2, the variant of concern 202012/01
or lineage B. 1.1. 7, has emerged in the UK. We aimed to estimate the risk of critical care …
or lineage B. 1.1. 7, has emerged in the UK. We aimed to estimate the risk of critical care …
Emergence of SARS-CoV-2 variants in the world: how could this happen?
A Parra-Lucares, P Segura, V Rojas, C Pumarino… - Life, 2022 - mdpi.com
The COVID-19 pandemic has had a significant global impact, with more than 280,000,000
people infected and 5,400,000 deaths. The use of personal protective equipment and the …
people infected and 5,400,000 deaths. The use of personal protective equipment and the …
Profiling CD8+ T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants
Cellular immunity is important in determining the disease severity of COVID-19 patients.
However, current understanding of SARS-CoV-2 epitopes mediating cellular immunity is …
However, current understanding of SARS-CoV-2 epitopes mediating cellular immunity is …
Lives saved and hospitalizations averted by COVID-19 vaccination in New York City: a modeling study
Background Following the start of COVID-19 vaccination in New York City (NYC), cases
have declined over 10-fold from the outbreak peak in January 2020, despite the emergence …
have declined over 10-fold from the outbreak peak in January 2020, despite the emergence …