Traffic accidents and falling objects are responsible for most spinal cord injuries (SCIs). SCI
is characterized by high disability and tends to occur among the young, seriously affecting …

Background/Aims: Multiple sclerosis (MS) is a prototypical autoimmune central nervous
system (CNS) disease. Particularly progressive forms of MS (PMS) show significant …

Stroke causes devastating sensory-motor deficits and long-term disability due to disruption
of descending motor pathways. Restoration of these functions enables independent living …

The anticonvulsant pregabalin promotes neural regeneration in a mouse model of spinal
cord injury (SCI). We have also previously observed that anticonvulsants improve motor …

Peripheral diabetic neuropathy develops in diabetic patients. The current study tested the
antiallodynic and antihyperalgesic effects of the anticonvulsant drug, levetiracetam …

Gabapentin (GBP) is an anticonvulsant that acts at the α2δ-1 submit of the L-type calcium
channel. It is recently reported that GBP is a potent inhibitor of thrombospondin (TSP) …

Background The infliction of a traumatic spinal cord injury (SCI) propagates damage that
occurs in 2 stages. The first phase of trauma develops from the initial mechanical insult. The …

Developmental cortical malformations (DCMs) result from pre-and perinatal insults, as well
as genetic mutations. Hypoxia, viral infection, and traumatic injury are the most common …

Trauma in spinal cord injury often results in massive damage to the white matter and in
damage to myelin that results in a severe phagocyte-rich infiltration apparently directed at …

Object Extensive research has been focused on neuroprotection after spinal cord trauma to
alleviate the effects of secondary injury. This study aims to investigate the neuroprotective …