The role of matrix metalloproteinases in the epithelial‐mesenchymal transition of hepatocellular carcinoma
C Scheau, IA Badarau, R Costache… - Analytical cellular …, 2019 - Wiley Online Library
The epithelial‐mesenchymal transition (EMT) is a transformation process mandatory for the
local and distant progression of many malignant tumors, including hepatocellular carcinoma …
local and distant progression of many malignant tumors, including hepatocellular carcinoma …
[HTML][HTML] Apolipoprotein AI (ApoA-I), immunity, inflammation and cancer
K Georgila, D Vyrla, E Drakos - Cancers, 2019 - mdpi.com
Apolipoprotein AI (ApoA-I), the major protein component of high-density lipoproteins (HDL)
is a multifunctional protein, involved in cholesterol traffic and inflammatory and immune …
is a multifunctional protein, involved in cholesterol traffic and inflammatory and immune …
[HTML][HTML] HDL and cancer-causality still needs to be confirmed? Update 2020
An inverse correlation between high-density lipoprotein cholesterol (HDL-C) and cancer risk
has been shown by several epidemiological studies. Some studies have even suggested …
has been shown by several epidemiological studies. Some studies have even suggested …
[HTML][HTML] Proteomics-based identification of dysregulated proteins in breast cancer
Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …
[HTML][HTML] Proteomics-Based identification of dysregulated proteins and biomarker discovery in invasive ductal carcinoma, the most common breast cancer subtype
Invasive ductal carcinoma (IDC) is the most common histological subtype of malignant
breast cancer (BC), and accounts for 70–80% of all invasive BCs. IDC demonstrates great …
breast cancer (BC), and accounts for 70–80% of all invasive BCs. IDC demonstrates great …
[HTML][HTML] Proteomics of muscle microdialysates identifies potential circulating biomarkers in facioscapulohumeral muscular dystrophy
V Corasolla Carregari, M Monforte, G Di Maio… - International journal of …, 2020 - mdpi.com
Facioscapulohumeral muscular dystrophy (FSHD) is caused by a complex epigenetic
mechanism finally leading to the misexpression of DUX4 in skeletal muscle. Detecting DUX4 …
mechanism finally leading to the misexpression of DUX4 in skeletal muscle. Detecting DUX4 …
[HTML][HTML] Apolipoproteins: New players in cancers
Y He, J Chen, Y Ma, H Chen - Frontiers in Pharmacology, 2022 - frontiersin.org
Apolipoproteins (APOs), the primary protein moiety of lipoproteins, are known for their
crucial role in lipid traffic and metabolism. Despite extensive exploration of APOs in …
crucial role in lipid traffic and metabolism. Despite extensive exploration of APOs in …
CDC7 as a novel biomarker and druggable target in cancer
R Liu, Y Huang - Clinical and Translational Oncology, 2022 - Springer
Due to the bottlenecks encountered in traditional treatment for tumor, more effective drug
targets need to be developed. Cell division cycle 7 kinase plays an important role in DNA …
targets need to be developed. Cell division cycle 7 kinase plays an important role in DNA …
Deciphering a proteomic signature for the early detection of breast cancer from breast milk: the role of quantitative proteomics
Introduction Breast cancer is one of the most prevalent cancers among women in the United
States. Current research regarding breast milk has been focused on the composition and its …
States. Current research regarding breast milk has been focused on the composition and its …
[HTML][HTML] Aberrant super-enhancer-driven oncogene ENC1 promotes the radio-resistance of breast carcinoma
L Li, N Wang, M Zhu, Y Xiong, F Wang, G Guo… - Cell Death & …, 2021 - nature.com
Poor response of tumors to radiotherapy is a major clinical obstacle. Because of the dynamic
characteristics of the epigenome, identification of possible epigenetic modifiers may be …
characteristics of the epigenome, identification of possible epigenetic modifiers may be …