The case for periodontitis in the pathogenesis of rheumatoid arthritis

J Potempa, P Mydel, J Koziel - Nature Reviews Rheumatology, 2017 - nature.com
Rheumatoid arthritis (RA), an autoimmune disease that affects∼ 1% of the human
population, is driven by autoantibodies that target modified self-epitopes, whereas∼ 11% of …

Periodontitis and rheumatoid arthritis: What have we learned about their connection and their treatment?

J González‐Febles, M Sanz - Periodontology 2000, 2021 - Wiley Online Library
Rheumatoid arthritis and periodontitis are chronic inflammatory diseases defined
respectively by the destruction of the articular cartilage and tooth‐supporting periodontal …

[HTML][HTML] Periodontitis and periodontopathic bacteria as risk factors for rheumatoid arthritis: A review of the last 10 years

T Kobayashi, PM Bartold - Japanese Dental Science Review, 2023 - Elsevier
Rheumatoid arthritis (RA) is characterized by chronic inflammatory destruction of joint tissue
and is caused by an abnormal autoimmune response triggered by interactions between …

Periodontitis and rheumatoid arthritis: an update 2012‐2017

PM Bartold, I Lopez‐Oliva - Periodontology 2000, 2020 - Wiley Online Library
Rheumatoid arthritis and chronic periodontitis are both chronic inflammatory diseases
characterized by an exacerbated inflammatory reaction that leads to destruction of bone and …

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

I Lopez‐Oliva, J Malcolm, S Culshaw - Periodontology 2000, 2024 - Wiley Online Library
Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to
manage patients with both periodontitis and RA. This review seeks to provide an update on …

Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4

C Gajendran, S Fukui, NM Sadhu, M Zainuddin… - Scientific Reports, 2023 - nature.com
Protein arginine deiminases (PAD) 4 is an enzyme that catalyzes citrullination of protein and
its role in autoimmune diseases has been established through clinical genetics and gene …

Periodontitis and rheumatoid arthritis: the same inflammatory mediators?

F Ceccarelli, M Saccucci, G Di Carlo… - Mediators of …, 2019 - Wiley Online Library
The strict link between periodontitis (PD) and rheumatoid arthritis (RA) has been widely
demonstrated by several studies. PD is significantly more frequent in RA patients in …

Pros and cons of causative association between periodontitis and rheumatoid arthritis

J Koziel, J Potempa - Periodontology 2000, 2022 - Wiley Online Library
Research in recent decades has brought significant advancements in understanding of the
molecular basis of the etiology of autoimmune diseases, including rheumatoid arthritis, a …

Periodontal complications with age

GR Persson - Periodontology 2000, 2018 - Wiley Online Library
The present literature review on periodontal complications in aging focuses on the
diagnosis, etiology and development of periodontal complications as a complete entity. In …

Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells …

N Sherina, C de Vries, N Kharlamova, N Sippl… - Frontiers in …, 2022 - frontiersin.org
Based on the epidemiological link between periodontitis and rheumatoid arthritis (RA), and
the unique feature of the periodontal bacterium Porphyromonas gingivalis to citrullinate …