Polymorphism in the DNA repair enzyme XRCC1: utility of current database and implications for human health risk assessment
G Ginsberg, K Angle, K Guyton, B Sonawane - Mutation Research/Reviews …, 2011 - Elsevier
Genetic polymorphisms are increasingly recognized as sources of variability not only in
toxicokinetic but also in toxicodynamic response to environmental agents. XRCC1 is …
toxicokinetic but also in toxicodynamic response to environmental agents. XRCC1 is …
[HTML][HTML] Indian studies on genetic polymorphisms and cancer risk
Genetic influences on cancer development have been extensively investigated during the
last decade following publication of human genome sequence. The present review …
last decade following publication of human genome sequence. The present review …
Association of RAD51, XRCC1, XRCC2, and XRCC3 Polymorphisms with Risk of Breast Cancer
P Gupta, V Sambyal, K Guleria, MS Uppal… - Genetic Testing and …, 2023 - liebertpub.com
Background: DNA repair genes are among the low-penetrance genes implicated in breast
cancer. However variants of DNA repair genes may alter their protein function thus leading …
cancer. However variants of DNA repair genes may alter their protein function thus leading …
Associated risk of XRCC1 and XPD cross talk and life style factors in progression of head and neck cancer in north Indian population
A Kumar, MC Pant, HS Singh, S Khandelwal - … Research/Fundamental and …, 2012 - Elsevier
Effective DNA repair machinery ensures maintenance of genomic integrity. Environmental
insults, ageing and replication errors necessitate the need for proper DNA repair systems …
insults, ageing and replication errors necessitate the need for proper DNA repair systems …
Association of XRCC1, XRCC2 and XRCC3 Gene Polymorphism with Esophageal Cancer Risk
J Kaur, V Sambyal, K Guleria, NR Singh… - Clinical and …, 2020 - Taylor & Francis
Aim The X-ray repair cross-complementing (XRCC) gene polymorphisms influence
esophageal carcinogenesis by altering the DNA repair capacity. The present study was …
esophageal carcinogenesis by altering the DNA repair capacity. The present study was …
Polymorphisms in DNA repair genes XRCC1, XRCC3 and XPD, and colorectal cancer risk: a case–control study in an Indian population
J Wang, Y Zhao, J Jiang, V Gajalakshmi… - Journal of cancer …, 2010 - Springer
Purpose Genetic polymorphisms in DNA repair genes may influence variations in individual
DNA repair capacity, which could be associated with the development of cancer. We …
DNA repair capacity, which could be associated with the development of cancer. We …
[HTML][HTML] Statistically significant association of the single nucleotide polymorphism (SNP) rs13181 (ERCC2) with predisposition to Squamous Cell Carcinomas of the …
AK Mitra, N Singh, VK Garg, R Chaturvedi… - Journal of Experimental …, 2009 - Springer
Background Non-synonymous single nucleotide polymorphisms (SNPs) within vital DNA
repair genes may cause reduction of activity leaving the genome unrepaired resulting in …
repair genes may cause reduction of activity leaving the genome unrepaired resulting in …
Genetic polymorphisms of DNA repair genes and DNA repair capacity related to aflatoxin b1 (AFB1)-induced DNA damages
Q Xia, XY Huang, F Xue, JJ Zhang, B Zhai… - … directions in DNA …, 2013 - books.google.com
AflatoxinB1 (AFB1) isanimportantaflatoxinproducedbysomestrai…‐lus parasiticus and
Aspergillus flavus [1-3]. This aflatoxin was discovered as a contaminant of …
Aspergillus flavus [1-3]. This aflatoxin was discovered as a contaminant of …
[HTML][HTML] XPD Lys751Gln polymorphism and esophageal cancer risk: a meta-analysis involving 2288 cases and 4096 controls
L Yuan, D Cui, EJ Zhao, CZ Jia, LD Wang… - World journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To evaluate the association between xeroderma pigmentosum group D (XPD), genetic
polymorphism Lys751Gln and esophageal cancer risk. METHODS: We searched PubMed …
polymorphism Lys751Gln and esophageal cancer risk. METHODS: We searched PubMed …
CYP17 gene polymorphism and its association in north Indian prostate cancer patients
RC Sobti, L Gupta, H Thakur, A Seth… - Anticancer …, 2009 - ar.iiarjournals.org
Background: The CYP17 gene codes for the cytochrome P450c17a enzyme, which
mediates two key steps in sex steroid synthesis In this study, the association between …
mediates two key steps in sex steroid synthesis In this study, the association between …