IgG3 comprises only a minor fraction of IgG and has remained relatively understudied until
recent years. Key physiochemical characteristics of IgG3 include an elongated hinge region …

The human IgG3 subclass is conspicuously absent among the formats for approved
monoclonal antibody therapies and Fc fusion protein biologics. Concern about the potential …

The emergence of single nucleus RNA sequencing (snRNA-seq) offers to revolutionize the
study of Alzheimer's disease (AD). Integration with complementary multiomics data such as …

Background. Enteric fever caused by Salmonella Typhi remains a major public health
problem in developing countries. Typbar-TCV is a single-dose typhoid Vi polysaccharide …

Humans have four IgG antibody subclasses that selectively or differentially engage immune
effector molecules to protect against infections. Although IgG1 has been studied in detail …

Phagocytosis is a conserved cellular response among metazoans. Opsonins are some
molecules that label targets to increase their susceptibility to phagocytosis. Opsonins are …

Naturally acquired humoral immunity to the malarial parasite Plasmodium falciparum can
protect against disease, although the precise mechanisms remain unclear. Although …

As cells with aberrant force-generating phenotypes can directly lead to disease, cellular
force-generation mechanisms are high-value targets for new therapies. Here, we show that …

We previously evaluated Wilms' tumor gene 1 (WT1) peptide vaccination in a large number
of patients with leukemia or solid tumors and have reported that HLA‐A* 24: 02 restricted, 9 …

The hepatopancreas is an important digestive and immune organ in crustacean. There were
low but stable numbers of microbes living in the hemolymph of crustacean, whereas the …