The great apes (chimpanzees, bonobos, gorillas, and orangutans) are our closest relatives.
Despite the many similarities, there are significant differences in aging among apes …

CCR5, a chemokine receptor central for orchestrating lymphocyte/cell migration to the sites
of inflammation and to the immunosurveillance, is involved in the pathogenesis of a wide …

Walking—humans' most fundamental form of moderate intensity physical activity—is
associated with reduced risks of morbidity and mortality. Evolutionary perspectives have …

Chimpanzees in west central Africa (Pan troglodytes troglodytes) are endemically infected
with simian immunodeficiency viruses (SIVcpz Ptt) that have crossed the species barrier to …

Background Coagulation and innate immunity have been linked together for at least 450
million years of evolution. Sepsis, one of the world's leading causes of death, is probably the …

Simian immunodeficiency virus of chimpanzees (SIVcpz) is the ancestor of human
immunodeficiency virus type 1 (HIV-1), the etiologic agent of acquired immunodeficiency …

Pathogenesis studies of SIV infection have not been performed to date in wild monkeys due
to difficulty in collecting and storing samples on site and the lack of analytical reagents …

What is the likelihood that humans will ever determine if other animals engage in higher-
order thinking? In examining what has happened in the twenty years since the publication of …

Background The human apolipoprotein E (APOE) gene is polymorphic, with three primary
alleles (E2, E3, E4) that differ at two key non-synonymous sites. These alleles are …

Information about responses to death in nonhuman primates is important for evolutionary
thanatology. This paper reviews the major causes of death in chimpanzees, and how these …