One of the significant challenges remaining in the field of drug delivery is insufficient
targeting of diseased tissues or cells. While efforts to perform targeted drug delivery by …

Advances in synthetic biology have provided genetic tools to reprogram cells to obtain a
variety of desired cellular functions. These include tools to enable the customization of cells …

Bidirectional optogenetic control of yeast gene expression has great potential for
biotechnological applications. Our group has developed optogenetic inverter circuits that …

Tissue engineering approaches, with the goals of replacing or recovering damaged or
diseased tissues, or of reconstituting tissues in vitro for disease modeling and drug …

A primary focus of the rapidly growing field of plant synthetic biology is to develop
technologies to precisely regulate gene expression and engineer complex genetic circuits …

Persistent and complex problems arising with respect to human physiology and pathology
have led to intense investigation into therapies and tools that permit more targeted outcomes …

Expanding the genetic toolbox for prokaryotic synthetic biology is a promising strategy for
enhancing the dynamic range of gene expression and enabling new engineered …

Binary expression systems are useful genetic tools for experimentally labeling or
manipulating the function of defined cells. The Q-system is a repressible binary expression …

Synthetic biologists use engineering principles to design and construct genetic circuits for
programming cells with novel functions. A bottom-up approach is commonly used to design …

The development of synthetic biology has enabled massive progress in biotechnology and
in approaching research questions from a brand-new perspective. In particular, the design …