[HTML][HTML] Experimental and clinical treatment of Chagas disease: a review
PAS Junior, I Molina, SMF Murta… - The American journal …, 2017 - ncbi.nlm.nih.gov
Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi that infects a
broad range of triatomines and mammalian species, including man. It afflicts 8 million …
broad range of triatomines and mammalian species, including man. It afflicts 8 million …
[HTML][HTML] Advances in the treatment of Chagas disease: Promising new drugs, plants and targets
P García-Huertas, N Cardona-Castro - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Chagas disease, caused by Trypanosoma cruzi, is treated with only two drugs;
benznidazole and nifurtimox. These drugs have some disadvantages, including their …
benznidazole and nifurtimox. These drugs have some disadvantages, including their …
Current drug therapy and pharmaceutical challenges for Chagas disease
One of the most significant health problems in the American continent in terms of human
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …
[HTML][HTML] Current trends in the pharmacological management of Chagas disease
V Ribeiro, N Dias, T Paiva, L Hagström-Bex… - International Journal for …, 2020 - Elsevier
Chagas disease (CD) is a tropical neglected illness, affecting mainly populations of low
socioeconomic status in Latin America. An estimated 6 to 8 million people worldwide are …
socioeconomic status in Latin America. An estimated 6 to 8 million people worldwide are …
CYP51 as drug targets for fungi and protozoan parasites: past, present and future
GI Lepesheva, L Friggeri, MR Waterman - Parasitology, 2018 - cambridge.org
The efficiency of treatment of human infections with the unicellular eukaryotic pathogens
such as fungi and protozoa remains deeply unsatisfactory. For example, the mortality rates …
such as fungi and protozoa remains deeply unsatisfactory. For example, the mortality rates …
Efficacy and safety of fexinidazole for treatment of chronic indeterminate Chagas disease (FEXI-12): a multicentre, randomised, double-blind, phase 2 trial
MJ Pinazo, C Forsyth, I Losada, ET Esteban… - The Lancet Infectious …, 2024 - thelancet.com
Background More than six million people worldwide, particularly in vulnerable communities
in Latin America, are infected with Trypanosoma cruzi, the causative agent of Chagas …
in Latin America, are infected with Trypanosoma cruzi, the causative agent of Chagas …
[HTML][HTML] Therapeutic Potential of Marine-Derived Cyclic Peptides as Antiparasitic Agents
R Ribeiro, L Costa, E Pinto, E Sousa, C Fernandes - Marine Drugs, 2023 - mdpi.com
Parasitic diseases still compromise human health. Some of the currently available
therapeutic drugs have limitations considering their adverse effects, questionable efficacy …
therapeutic drugs have limitations considering their adverse effects, questionable efficacy …
[HTML][HTML] Infecciones por parásitos más frecuentes y su manejo
BW Apt - Revista Médica Clínica Las Condes, 2014 - Elsevier
Las enfermedades parasitarias constituyen un problema de salud pública por su alta
frecuencia en países en vías de desarrollo y por la presencia en países desarrollados …
frecuencia en países en vías de desarrollo y por la presencia en países desarrollados …
Investigation of a combination of amiodarone and itraconazole for treatment of American trypanosomiasis (Chagas disease) in dogs
R Madigan, S Majoy, K Ritter… - Journal of the …, 2019 - Am Vet Med Assoc
OBJECTIVE To evaluate clinical, serologic, parasitological, and histologic outcomes of dogs
with naturally occurring Trypanosoma cruzi infection treated for 12 months with amiodarone …
with naturally occurring Trypanosoma cruzi infection treated for 12 months with amiodarone …
Stairway to heaven or hell? Perspectives and limitations of Chagas disease chemotherapy
K Salomao… - Current Topics in …, 2016 - ingentaconnect.com
In this review, we intend to provide a general view of the evolution of experimental studies in
the area of chemotherapy for Chagas disease. We can follow the process of drug …
the area of chemotherapy for Chagas disease. We can follow the process of drug …