Advances in the immunology and genetics of leprosy
Z Mi, H Liu, F Zhang - Frontiers in immunology, 2020 - frontiersin.org
Leprosy, a disease caused by the intracellular parasite Mycobacterium leprae or
Mycobacterium lepromatosis, has affected humans for more than 4,000 years and is a …
Mycobacterium lepromatosis, has affected humans for more than 4,000 years and is a …
Pauci-and multibacillary leprosy: two distinct, genetically neglected diseases
J Gaschignard, AV Grant, NV Thuc… - PLoS neglected …, 2016 - journals.plos.org
After sustained exposure to Mycobacterium leprae, only a subset of exposed individuals
develops clinical leprosy. Moreover, leprosy patients show a wide spectrum of clinical …
develops clinical leprosy. Moreover, leprosy patients show a wide spectrum of clinical …
[HTML][HTML] Ancient genomes reveal structural shifts after the arrival of Steppe-related ancestry in the Italian Peninsula
T Saupe, F Montinaro, C Scaggion, N Carrara… - Current Biology, 2021 - cell.com
Across Europe, the genetics of the Chalcolithic/Bronze Age transition is increasingly
characterized in terms of an influx of Steppe-related ancestry. The effect of this major shift on …
characterized in terms of an influx of Steppe-related ancestry. The effect of this major shift on …
Genetic history of Cambridgeshire before and after the Black Death
R Hui, CL Scheib, E D'Atanasio, SA Inskip… - Science …, 2024 - science.org
The extent of the devastation of the Black Death pandemic (1346–1353) on European
populations is known from documentary sources and its bacterial source illuminated by …
populations is known from documentary sources and its bacterial source illuminated by …
Leprosy susceptibility: genetic variations regulate innate and adaptive immunity, and disease outcome
CC Cardoso, AC Pereira, C de Sales Marques… - Future …, 2011 - Taylor & Francis
The past few years have been very productive concerning the identification of genes
associated with leprosy. Candidate gene strategies using both case–control and family …
associated with leprosy. Candidate gene strategies using both case–control and family …
Mycobacterium leprae–host-cell interactions and genetic determinants in leprosy: an overview
RO Pinheiro, J de Souza Salles, EN Sarno… - Future …, 2011 - Taylor & Francis
Leprosy, also known as Hansen's disease, is a chronic infectious disease caused by
Mycobacterium leprae in which susceptibility to the mycobacteria and its clinical …
Mycobacterium leprae in which susceptibility to the mycobacteria and its clinical …
Host-related laboratory parameters for leprosy reactions
Y Luo, M Kiriya, K Tanigawa, A Kawashima… - Frontiers in …, 2021 - frontiersin.org
Leprosy reactions are acute inflammatory episodes that complicate the course of a
Mycobacterium leprae infection and are the major cause of leprosy-associated pathology …
Mycobacterium leprae infection and are the major cause of leprosy-associated pathology …
Role of vitamin D in cytotoxic T lymphocyte immunity to pathogens and cancer
The discovery of vitamin D receptor (VDR) expression in immune cells has opened up a new
area of research into immunoregulation by vitamin D, a niche that is distinct from its classical …
area of research into immunoregulation by vitamin D, a niche that is distinct from its classical …
Association of the LRRK2 genetic polymorphisms with leprosy in Han Chinese from Southwest China
Leprosy is a chronic infectious and neurological disease that is caused by infection of
Mycobacterium leprae (M. leprae). A recent genome-wide association study indicated a …
Mycobacterium leprae (M. leprae). A recent genome-wide association study indicated a …
[HTML][HTML] Risk factors for leprosy reactions in three endemic countries
DM Scollard, CMT Martelli, MMA Stefani… - The American journal …, 2015 - ncbi.nlm.nih.gov
The objective of this study was to ascertain risk factors for complications (reactions or
neuritis) in leprosy patients at the time of diagnosis in three leprosy-endemic countries …
neuritis) in leprosy patients at the time of diagnosis in three leprosy-endemic countries …