Background: Linezolid is the first oxazolidinone anti-infective agent marketed in the United
States. It is indicated for the treatment of nosocomial pneumonia, complicated skin and skin …

Linezolid (Zyvox), the first of a new class of antibiotics, the oxazolidinones, is approved for
treatment of Gram-positive bacterial infections, including resistant strains. The disposition of …

1. Linezolid (ZYVOX™), the first of a new class of antibiotics, the oxazolidinones, is
approved for treatment of Gram-positive bacterial infections. 2. The aim was to determine the …

Background. Linezolid is an oxazolidinone antibiotic with excellent in vitro activity against a
number of Gram-positive organisms including antibiotic-resistant isolates. The safety and …

We describe a new method for the measurement of antimicrobial concentrations in the
biofilm associated with the endoluminal surface of intravascular catheters. We quantified …

The in vivo effectiveness of oxazolidinones eperezolid (U-100592) and linezolid (U-100766)
against one strain each of Enterococcus faecalis and vancomycin-resistant Enterococcus …

INTRODUCTION: The treatment of postoperative mediastinitis is very important because of
its high morbidity, mortality, and increased hospital stay and hospital costs. The aims of our …

BACKGROUND: We aimed to investigate the therapeutic efficacy of linezolid in an
experimental mediastinitis model and to compare it with vancomycin, which is commonly …

During the last decade, gram-positive bacteria have emerged as important nosocomial and
community-acquired pathogens. Development of antimicrobial resistance has complicated …

The incidence of nosocomial infections from Gram-positive pathogens has been increasing
in the last two decades, alongside the development of antibiotic resistance in many bacteria …