Granulosa cells are essential for follicle initiation and development, and their abnormal
function or apoptosis is a crucial factor leading to follicular atresia. A state of oxidative stress …

Autophagy is a mechanism that exists in all eukaryotes under a variety of physiological and
pathological conditions. In the mammalian ovaries, less than 1% of follicles ovulate …

More than 99% of ovarian follicles undergo atresia in mammals, but the mechanism of
follicular atresia remains to be elucidated. In this study, we explored microRNA (miRNA) …

The follicle is the functional unit of the ovary, whereby ovarian development is largely
dependent on the development of the follicles themselves. The activation, growth, and …

Tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) are cytokines that are involved
in the development, proliferation and apoptosis of ovarian follicular cells in domestic …

Our understanding of the post-transcriptional mechanisms involved in follicular atresia is
limited; however, an important development has been made in understanding the biological …

The endoplasmic reticulum (ER) is the principal organelle responsible for several specific
cellular functions including synthesis and folding of secretory or membrane proteins, lipid …

Although previous studies have suggested that cumulus cells (CCs) accelerate oocyte aging
by secreting soluble and heat-sensitive paracrine factors, the factors involved are not well …

The present short review demonstrates an important role of different cytokines (colony
stimulating factors, tumor necrosis factors, interleukins, anti-Mullerian hormone, inhibin …

Follicular atresia mainly results from apoptosis of granulosa cells (GCs). Our previous
microRNA array data indicated that the miRNA let-7g level increases significantly during …