Chalcones: Synthetic chemistry follows where nature leads

HA Jasim, L Nahar, MA Jasim, SA Moore, KJ Ritchie… - Biomolecules, 2021 - mdpi.com
Chalcones belong to the flavonoid class of phenolic compounds. They form one of the
largest groups of bioactive natural products. The potential anticancer, anti-inflammatory …

Exploring the Leaves of Annona muricata L. as a Source of Potential Anti-inflammatory and Anticancer Agents

SM Abdul Wahab, I Jantan, MA Haque… - Frontiers in …, 2018 - frontiersin.org
The use of anti-inflammatory natural products to treat inflammatory disorders for cancer
prevention and therapy is an appealing area of interest in the last decades. Annona …

Recent updates on anti-inflammatory and antimicrobial effects of furan natural derivatives

M Alizadeh, M Jalal, K Hamed, A Saber… - Journal of …, 2020 - Taylor & Francis
The furan nucleus is found in a large number of biologically active materials. In recent years,
many natural furan derivatives were isolated and their biological effects were investigated. In …

Naturally occurring immunomodulators with antitumor activity: An insight on their mechanisms of action

SIA Mohamed, I Jantan, MA Haque - International Immunopharmacology, 2017 - Elsevier
Natural products with immunomodulatory activity are widely used in treatment of many
diseases including autoimmune diseases, inflammatory disorders in addition to cancer …

Mechanistic insight into immunomodulatory effects of food-functioned plant secondary metabolites

ASM Ali Reza, MS Nasrin, MA Hossen… - Critical reviews in …, 2023 - Taylor & Francis
Medicinally important plant-foods offer a balanced immune function, which is essential for
protecting the body against antigenic invasion, mainly by microorganisms …

Antitumor potential of immunomodulatory natural products

G Nuzzo, G Senese, C Gallo, F Albiani, L Romano… - Marine Drugs, 2022 - mdpi.com
Cancer is one of the leading causes of death globally. Anticancer drugs aim to block tumor
growth by killing cancerous cells in order to prevent tumor progression and metastasis …

Structural studies of β-diketones and their implications on biological effects

PE Hansen - Pharmaceuticals, 2021 - mdpi.com
The paper briefly summarizes methods to determine the structure of β-diketones with
emphasis on NMR methods. Density functional calculations are also briefly treated …

An overview of NRF2-activating compounds bearing α, β-unsaturated moiety and their antioxidant effects

MC Egbujor, B Buttari, E Profumo… - International Journal of …, 2022 - mdpi.com
The surge of scientific interest in the discovery of Nuclear Factor Erythroid 2 (NFE2)-Related
Factor 2 (NRF2)-activating molecules underscores the importance of NRF2 as a therapeutic …

Recent advances of analogues of curcumin for treatment of cancer

S Zhao, C Pi, Y Ye, L Zhao, Y Wei - European Journal of Medicinal …, 2019 - Elsevier
Curcumin (CU), an edible natural pigment from Curcuma Longa, has demonstrated
extensive anti-tumor effect in vivo and in vitro. With the property of reversing drug resistance …

Drug discovery from natural products–Old problems and novel solutions for the treatment of neurodegenerative diseases

U Maitra, C Stephen, LM Ciesla - Journal of pharmaceutical and biomedical …, 2022 - Elsevier
The use of natural products has been shown to be a fruitful approach in the discovery of
novel pharmaceuticals. In fact, many currently approved drugs originated from compounds …