Objectives Acute kidney injury (AKI) is increasingly recognized as a source of poor patient
outcomes after cardiac surgery. The purpose of the present report is to provide perioperative …

Cardiac surgery on cardiopulmonary bypass (CPB) is associated with postoperative renal
dysfunction, one of the most common complications of this surgical cohort. Acute kidney …

Background Acute kidney injury (AKI) is a major complication following cardiac surgery that
substantially increases morbidity and mortality. Current diagnostic guidelines based on …

Background: Ultrafiltration is used with cardiopulmonary bypass to reduce the effects of
hemodilution and restore electrolyte balance. We performed a systematic review and meta …

Fluid therapy is an integral component of perioperative management. In light of emerging
evidence in this area, the Perioperative Quality Initiative (POQI) convened an international …

Liver fibrosis is a chronic liver injury that leads to liver cirrhosis and liver cancer. Ring finger
protein 20 (RNF20), also named as E3 ubiquitin-protein ligase BRE1A, has been reported to …

Background Ultrafiltration (UF) is a common practice during cardiopulmonary bypass (CPB)
where it is used as a blood management strategy to reduce red blood cell (RBC) transfusion …

Background Postoperative pulmonary complications increase mortality after cardiac surgery.
Conventional ultrafiltration may reduce pulmonary complications by removing mediators of …

Introduction Intraoperative ultrafiltration (UF) is a procedure used during cardiopulmonary
bypass (CPB) to reduce haemodilution and prevent excessive blood transfusion. However …

Background: Conventional ultrafiltration (CUF) during cardiopulmonary bypass (CPB) is
utilized to minimize hemodilution. However, removing high volumes leads to tissue …