Faster, better, and cheaper: harnessing microfluidics and mass spectrometry for biotechnology
NS Ha, M de Raad, A Golini, CJ Petzold… - RSC chemical …, 2021 - pubs.rsc.org
High-throughput screening technologies are widely used for elucidating biological activities.
These typically require trade-offs in assay specificity and sensitivity to achieve higher …
These typically require trade-offs in assay specificity and sensitivity to achieve higher …
Recent progress toward microfluidic quality control testing of radiopharmaceuticals
NS Ha, S Sadeghi, RM Van Dam - Micromachines, 2017 - mdpi.com
Radiopharmaceuticals labeled with short-lived positron-emitting or gamma-emitting isotopes
are injected into patients just prior to performing positron emission tomography (PET) or …
are injected into patients just prior to performing positron emission tomography (PET) or …
The current role of microfluidics in radiofluorination chemistry
KA Knapp, ML Nickels, HC Manning - Molecular Imaging and Biology, 2020 - Springer
The current utilization of positron emission tomography (PET) imaging is limited due to the
high costs associated with production facility start-up and operations; subsequently, there …
high costs associated with production facility start-up and operations; subsequently, there …
Microchip electrophoresis: A suitable analytical technique for pharmaceuticals quality control? A critical review
A Dispas, P Emonts, M Fillet - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Quality control (QC) is a major concern in the pharmaceutical industry to ensure medicines
quality and patient's safety. QC analysis are currently performed using several well-known …
quality and patient's safety. QC analysis are currently performed using several well-known …
Application of an electrokinetic backflow for enhancing pressure-driven charge based separations in sub-micrometer deep channels
In this article, we report significant improvements in the resolving power of pressure-driven
charge based separations performed in sub-micrometer deep glass channels upon …
charge based separations performed in sub-micrometer deep glass channels upon …
Toward miniaturized analysis of chemical identity and purity of radiopharmaceuticals via microchip electrophoresis
Miniaturized synthesis of positron emission tomography (PET) tracers is poised to offer
numerous advantages including reduced tracer production costs and increased availability …
numerous advantages including reduced tracer production costs and increased availability …
A novel planar grounded capacitively coupled contactless conductivity detector for microchip electrophoresis
J Wang, Y Liu, W He, Y Chen, H You - Micromachines, 2022 - mdpi.com
In the microchip electrophoresis with capacitively coupled contactless conductivity detection,
the stray capacitance of the detector causes high background noise, which seriously affects …
the stray capacitance of the detector causes high background noise, which seriously affects …
[HTML][HTML] Hydrodynamic injection for microchip electrophoresis: Development of an innovative passive system
A Dispas, P Emonts, D Vandormael, D Bernier… - Green Analytical …, 2024 - Elsevier
The world is facing challenges in terms of environmental sustainability and rising costs. In
this context, miniaturized equipment such as microfluidic devices can be used to manipulate …
this context, miniaturized equipment such as microfluidic devices can be used to manipulate …
Integration of high-resolution radiation detector for hybrid microchip electrophoresis
J Jones, NS Ha, AG Barajas… - Analytical …, 2020 - ACS Publications
For decades, there has been immense progress in miniaturizing analytical methods based
on electrophoresis to improve sensitivity and to reduce sample volumes, separation times …
on electrophoresis to improve sensitivity and to reduce sample volumes, separation times …
Use of capillary electrophoresis for the determination of impurities in preparations of fluorine-18 labelled PET radiopharmaceuticals
D Antuganov, Y Antuganova, T Zykova… - … of Pharmaceutical and …, 2019 - Elsevier
Fluorine-18 labelled radiotracers are the most common diagnostic agents employed in
positron emission tomography (PET). Despite well-established quality control (QC) …
positron emission tomography (PET). Despite well-established quality control (QC) …