Review and consensus on pharmacogenomic testing in psychiatry
The implementation of pharmacogenomic (PGx) testing in psychiatry remains modest, in part
due to divergent perceptions of the quality and completeness of the evidence base and …
due to divergent perceptions of the quality and completeness of the evidence base and …
Barriers to clinical adoption of pharmacogenomic testing in psychiatry: a critical analysis
CR Virelli, AG Mohiuddin, JL Kennedy - Translational psychiatry, 2021 - nature.com
Pharmacogenomics (PGx) is the study of genetic influences on an individual's response to
medications. Improvements in the quality and quantity of PGx research over the past two …
medications. Improvements in the quality and quantity of PGx research over the past two …
[HTML][HTML] Impact of pharmacogenomics on clinical outcomes in major depressive disorder in the GUIDED trial: a large, patient-and rater-blinded, randomized, controlled …
Current prescribing practices for major depressive disorder (MDD) produce limited treatment
success. Although pharmacogenomics may improve outcomes by identifying genetically …
success. Although pharmacogenomics may improve outcomes by identifying genetically …
Pharmacogenetic tests and depressive symptom remission: a meta-analysis of randomized controlled trials
CA Bousman, K Arandjelovic, SG Mancuso… - …, 2019 - Taylor & Francis
Aim: To conducted a systematic review and meta-analysis of prospective, randomized
controlled trials (RCTs) that examined pharmacogenetic-guided decision support tools …
controlled trials (RCTs) that examined pharmacogenetic-guided decision support tools …
Challenges and future prospects of precision medicine in psychiatry
M Manchia, C Pisanu, A Squassina… - Pharmacogenomics …, 2020 - Taylor & Francis
Precision medicine is increasingly recognized as a promising approach to improve disease
treatment, taking into consideration the individual clinical and biological characteristics …
treatment, taking into consideration the individual clinical and biological characteristics …
Effect of pharmacogenomics testing guiding on clinical outcomes in major depressive disorder: a systematic review and meta-analysis of RCT
X Wang, C Wang, Y Zhang, Z An - BMC psychiatry, 2023 - Springer
Background Pharmacogenomic testing guided treatment have been developed to guide
drug selection or conversion in major depressive disorder patients. Whether patients benefit …
drug selection or conversion in major depressive disorder patients. Whether patients benefit …
Economic evaluation in psychiatric pharmacogenomics: a systematic review
K Karamperis, M Koromina, P Papantoniou… - The …, 2021 - nature.com
Nowadays, many relevant drug–gene associations have been discovered, but
pharmacogenomics (PGx)-guided treatment needs to be cost-effective as well as clinically …
pharmacogenomics (PGx)-guided treatment needs to be cost-effective as well as clinically …
Genotype, phenotype, and medication recommendation agreement among commercial pharmacogenetic-based decision support tools
CA Bousman, BW Dunlop - The Pharmacogenomics Journal, 2018 - nature.com
The degree of agreement between four commercial pharmacogenetic-based decision
support tools (DSTs) was examined in five outpatients with major depressive disorder and at …
support tools (DSTs) was examined in five outpatients with major depressive disorder and at …
On the utilization of polygenic risk scores for therapeutic targeting
G Gibson - PLoS genetics, 2019 - journals.plos.org
The promise of personalized genomic medicine is that knowledge of a person's gene
sequences and activity will facilitate more appropriate medical interventions, particularly …
sequences and activity will facilitate more appropriate medical interventions, particularly …
Real-world impact of a pharmacogenomics-enriched comprehensive medication management program
JP Jarvis, AP Peter, M Keogh, V Baldasare… - Journal of Personalized …, 2022 - mdpi.com
The availability of clinical decision support systems (CDSS) and other methods for
personalizing medicine now allows evaluation of their real-world impact on healthcare …
personalizing medicine now allows evaluation of their real-world impact on healthcare …