This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Studies of neuropeptide and peptide hormone signaling are coming of age in Drosophila
due to rapid developments in molecular genetics approaches that overcome the difficulties …

The intracellular levels and spatial localizations of metabolites and peptides reflect the state
of a cell and its relationship to its surrounding environment. Moreover, the amounts and …

Hormones regulate development, as well as many vital processes in the daily life of an
animal. Many of these hormones are peptides that act at a higher hierarchical level in the …

About 150 clock neurons are clustered in different groups in the brain of Drosophila. Among
these clock neurons, some pigment‐dispersing factor (PDF)‐positive and PDF‐negative …

The bHLH transcription factor DIMMED has been associated with the differentiation of
peptidergic cells in Drosophila. However, whether all Drosophila peptidergic cells express …

The use of fruit flies has recently emerged as a powerful experimental paradigm to study the
core aspects of energy metabolism. The fundamental need for lipid and carbohydrate …

Single-cell analysis is gaining popularity in the field of mass spectrometry as a method for
analyzing protein and peptide content in cells. The spatial resolution of MALDI mass …

A complex cascade of events leads to the initiation and maintenance of a behavioral act in
response to both internally and externally derived stimuli. These events are part of a …

Peptidomics is the comprehensive characterization of peptides from biological sources
mainly by HPLC and mass spectrometry. Mass spectrometry allows the detection of a …