The DIRECT consortium and the REST-meta-MDD project: towards neuroimaging biomarkers of major depressive disorder

X Chen, B Lu, HX Li, XY Li, YW Wang… - …, 2022 - academic.oup.com
Despite a growing neuroimaging literature on the pathophysiology of major depressive
disorder (MDD), reproducible findings are lacking, probably reflecting mostly small sample …

Task-related neural activation abnormalities in patients with remitted major depressive disorder: a coordinate-based meta-analysis

Z Wang, Z Zou, J Xiao, P Wang, Y Luo, W Min… - Neuroscience & …, 2022 - Elsevier
Major depressive disorder (MDD) patients demonstrate abnormal neural activation even
after complete remission. Many task-related functional magnetic resonance imaging (fMRI) …

Linked patterns of symptoms and cognitive covariation with functional brain controllability in major depressive disorder

Q Li, Y Zhao, Y Hu, Y Liu, Y Wang, Q Zhang, F Long… - …, 2024 - thelancet.com
Background Controllability analysis is an approach developed for evaluating the ability of a
brain region to modulate function in other regions, which has been found to be altered in …

Disrupted intrinsic functional brain network in patients with late-life depression: Evidence from a multi-site dataset

W Tan, X Ouyang, D Huang, Z Wu, Z Liu, Z He… - Journal of Affective …, 2023 - Elsevier
Background Late-life depression (LLD) is a common and serious mental disorder, whose
neural mechanisms are not yet fully understood. In this study, we aimed to characterize LLD …

Abnormal cortical-striatal-thalamic-cortical circuit centered on the thalamus in MDD patients with somatic symptoms: Evidence from the REST-meta-MDD project

N Sun, M Liu, P Liu, A Zhang, C Yang, Z Liu, J Li… - Journal of affective …, 2023 - Elsevier
Objective Somatic symptoms are common comorbidities of major depressive disorder
(MDD), and negatively impact the course and severity of the disease. In order to enrich the …

Common and distinct functional brain network abnormalities in adolescent, early-middle adult, and late adult major depressive disorders

Y Long, X Li, H Cao, M Zhang, B Lu, Y Huang… - Psychological …, 2024 - cambridge.org
BackgroundThe age-related heterogeneity in major depressive disorder (MDD) has
received significant attention. However, the neural mechanisms underlying such …

Associations between somatic symptoms and remission of major depressive disorder: A longitudinal study in China

Y Jiang, D Zhu, X Huang, Y Li, Y Chen, Y Jiang… - Journal of psychiatric …, 2024 - Elsevier
Previous studies have documented negative associations between somatic symptoms and
remission of major depressive disorder (MDD). However, the correlations of specific somatic …

Lateralized grey matter volume changes in adolescents versus adults with major depression: SDM-PSI meta-analysis

E Zhang, AO Hauson, AA Pollard, B Meis… - Psychiatry Research …, 2023 - Elsevier
The current study is the first meta-analysis to examine grey matter volume (GMV) changes in
adolescents and across the lifespan in major depressive disorder (MDD). Seed-based d …

[HTML][HTML] Clinical MRI morphological analysis of functional seizures compared to seizure-naïve and psychiatric controls

WT Kerr, H Tatekawa, JK Lee, AH Karimi… - Epilepsy & Behavior, 2022 - Elsevier
Purpose Functional seizures (FS), also known as psychogenic nonepileptic seizures
(PNES), are physical manifestations of acute or chronic psychological distress. Functional …

Age-related decrease in default-mode network functional connectivity is accelerated in patients with major depressive disorder

S Tang, Z Wu, H Cao, X Chen, G Wu, W Tan… - Frontiers in Aging …, 2022 - frontiersin.org
Major depressive disorder (MDD) is a common psychiatric disorder which is associated with
an accelerated biological aging. However, little is known whether such process would be …