The host response to naturally-derived extracellular matrix biomaterials
AH Morris, DK Stamer, TR Kyriakides - Seminars in immunology, 2017 - Elsevier
Biomaterials based on natural materials including decellularized tissues and tissue-derived
hydrogels are becoming more widely used for clinical applications. Because of their native …
hydrogels are becoming more widely used for clinical applications. Because of their native …
Harnessing macrophage plasticity for tissue regeneration
Macrophages are versatile and plastic effector cells of the immune system, and contribute to
diverse immune functions including pathogen or apoptotic cell removal, inflammatory …
diverse immune functions including pathogen or apoptotic cell removal, inflammatory …
[HTML][HTML] Development of an accurate and proactive immunomodulatory strategy to improve bone substitute material-mediated osteogenesis and angiogenesis
Z Zheng, Y Chen, D Wu, J Wang, M Lv, X Wang… - Theranostics, 2018 - ncbi.nlm.nih.gov
Background: Treatment of large bone defects represents a major clinical problem worldwide.
Suitable bone substitute materials are commonly required to achieve successful bone …
Suitable bone substitute materials are commonly required to achieve successful bone …
[HTML][HTML] Human umbilical cord mesenchymal stem cell-derived extracellular vesicles alleviated silica induced lung inflammation and fibrosis in mice via circPWWP2A …
L Hou, Z Zhu, F Jiang, J Zhao, Q Jia, Q Jiang… - Ecotoxicology and …, 2023 - Elsevier
Silicosis is a progressive inflammatory disease with poorly defined mechanisms and limited
therapeutic options. Recent studies found that microRNAs (miRNAs) and circular RNAs …
therapeutic options. Recent studies found that microRNAs (miRNAs) and circular RNAs …
[HTML][HTML] Focus: genome editing: therapeutic peptide nucleic acids: principles, limitations, and opportunities
Since their invention in 1991, peptide nucleic acids (PNAs) have been used in a myriad of
chemical and biological assays. More recently, peptide nucleic acids have also been …
chemical and biological assays. More recently, peptide nucleic acids have also been …
miRNAs in tuberculosis: new avenues for diagnosis and host-directed therapy
Tuberculosis (TB) is one of the most fatal infectious diseases and a leading cause of
mortality, with 95% of these deaths occurring in developing countries. The causative agent …
mortality, with 95% of these deaths occurring in developing countries. The causative agent …
Non-viral nanocarriers for intracellular delivery of microRNA therapeutics
Z Bai, J Wei, C Yu, X Han, X Qin, C Zhang… - Journal of Materials …, 2019 - pubs.rsc.org
MicroRNAs are small regulatory noncoding RNAs that regulate various biological processes
associated with neurological disorders, cardiovascular diseases, cancer and viral infection …
associated with neurological disorders, cardiovascular diseases, cancer and viral infection …
Nanoparticle impact on innate immune cell pattern-recognition receptors and inflammasomes activation
Nanotechnology-based strategies can dramatically impact the treatment, prevention and
diagnosis of a wide range of diseases. Despite the unprecedented success achieved with …
diagnosis of a wide range of diseases. Despite the unprecedented success achieved with …
Non-viral based miR delivery and recent developments
AE Labatut, G Mattheolabakis - European Journal of Pharmaceutics and …, 2018 - Elsevier
Abstract miRNAs are promising therapeutic targets or tools for the treatment of numerous
diseases, with most prominently, cancer. The inherent capacity of these short nucleic acids …
diseases, with most prominently, cancer. The inherent capacity of these short nucleic acids …