Before a lead compound goes through a clinical trial, preclinical studies utilize two‐
dimensional (2D) in vitro models and animal models to study the pharmacodynamics and …

Methods to evaluate maternal-fetal transport across the placental barrier have generally
involved clinical observations after-the-fact, ex vivo perfused placenta studies, or in vitro …

Cardiac failure can be a life-threatening condition that, if left untreated, can have significant
consequences. Functional hydrogel has emerged as a promising platform for cardiac tissue …

Cellular dynamics are modeled by the 3D architecture and mechanics of the extracellular
matrix (ECM) and vice versa. These bidirectional cell‐ECM interactions are the basis for all …

Bioprinting is an emerging and promising technique for fabricating 3D cell-laden constructs
for various biomedical applications. In this paper, we employed 3D bioprinted GelMA-based …

Chronic, non-healing skin and soft tissue wounds are susceptible to infection, difficult to treat
clinically, and can severely reduce a patient's quality of life. A key aspect of this issue is the …

The field of organs-on-chips (OOCs) has experienced tremendous growth over the last
decade. However, the current main limiting factor for further growth lies in the fabrication …

Among many biomaterials, gelatin methacrylate (GelMA), a photocurable protein, has been
widely used in 3D bioprinting process owing to its excellent cellular responses …

STUDY QUESTION Does the upregulation of the zinc finger E-box binding homeobox 2
(ZEB2) transcription factor in human trophoblast cells lead to alterations in gene expression …

Research into the development of sustainable biomaterials is increasing in both interest and
global importance due to the increasing demand for materials with decreased environmental …