Although some long noncoding (lnc) RNAs are known since the 1950s, the past 25 years
have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The …

Circular RNAs (circRNAs) are formed in all domains of life and via different mechanisms.
There has been an explosion in the number of circRNA papers in recent years; however, as …

Circular RNAs (circRNAs) are a novel class of non-coding RNAs. They are single-stranded
RNA transcripts characterized with a closed loop structure making them resistant to …

Deregulation of RNA metabolism has emerged as one of the key events leading to the
degeneration of motor neurons (MNs) in Amyotrophic Lateral Sclerosis (ALS) disease …

Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs characterized by
their lack of 5′ caps and 3′ poly (A) tails. These molecules have garnered substantial …

Circular RNAs are abundant, covalently closed transcripts that arise in cells through back-
splicing and display distinct expression patterns across cells and developmental stages …

Stress granules (SG) are part of a cellular protection mechanism where untranslated
messenger RNAs and RNA-binding proteins are stored upon conditions of cellular stress …

Long noncoding RNAs (lncRNAs) are emerging as critical regulators of heart physiology
and disease, although the studies unveiling their modes of action are still limited to few …

Background Neurodegenerative disease is a collective term for a category of diseases that
are caused by neuronal dysfunction, such as Alzheimer's disease (AD), Parkinson's disease …

Altered autophagy is a hallmark of neurodegeneration but how autophagy is regulated in the
brain and dysfunctional autophagy leads to neuronal death has remained cryptic. Being a …