[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies
SV Bhujbal, B Mitra, U Jain, Y Gong, A Agrawal… - … Pharmaceutica Sinica B, 2021 - Elsevier
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
Spray drying formulation of amorphous solid dispersions
A Singh, G Van den Mooter - Advanced drug delivery reviews, 2016 - Elsevier
Spray drying is a well-established manufacturing technique which can be used to formulate
amorphous solid dispersions (ASDs) which is an effective strategy to deliver poorly water …
amorphous solid dispersions (ASDs) which is an effective strategy to deliver poorly water …
[图书][B] Polymorphism in the Pharmaceutical Industry: Solid Form and Drug Development
R Hilfiker, M Von Raumer - 2019 - books.google.com
" Polymorphism in the Pharmaceutical Industry-Solid Form and Drug Development"
highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus …
highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus …
Surface mobility of molecular glasses and its importance in physical stability
L Yu - Advanced drug delivery reviews, 2016 - Elsevier
Amorphous molecular materials (molecular glasses) are useful for drug delivery, bio-
preservation and organic electronics. A central issue in developing amorphous materials is …
preservation and organic electronics. A central issue in developing amorphous materials is …
The role of the carrier in the formulation of pharmaceutical solid dispersions. Part II: amorphous carriers
T Van Duong, G Van den Mooter - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Amorphous solid dispersions are considered as one of the most powerful
strategies to formulate poorly soluble drugs. They are made up of an active pharmaceutical …
strategies to formulate poorly soluble drugs. They are made up of an active pharmaceutical …
Solid-state properties and dissolution behaviour of tablets containing co-amorphous indomethacin–arginine
E Lenz, KT Jensen, LI Blaabjerg, K Knop… - European Journal of …, 2015 - Elsevier
Co-amorphous drug formulations provide the possibility to stabilize a drug in its amorphous
form by interactions with low molecular weight compounds, eg amino acids. Recent studies …
form by interactions with low molecular weight compounds, eg amino acids. Recent studies …
Current status of supersaturable self-emulsifying drug delivery systems
Self-emulsifying drug delivery systems (SEDDSs) are a vital strategy to enhance the
bioavailability (BA) of formulations of poorly water-soluble compounds. However, these …
bioavailability (BA) of formulations of poorly water-soluble compounds. However, these …
Crystallization tendency of pharmaceutical glasses: relevance to compound properties, impact of formulation process, and implications for design of amorphous solid …
K Kawakami - Pharmaceutics, 2019 - mdpi.com
Amorphous solid dispersions (ASDs) are important formulation strategies for improving the
dissolution process and oral bioavailability of poorly soluble drugs. Physical stability of a …
dissolution process and oral bioavailability of poorly soluble drugs. Physical stability of a …
Compression-induced crystallization of amorphous indomethacin in tablets: characterization of spatial heterogeneity by two-dimensional X-ray diffractometry
Tablets of amorphous indomethacin were compressed at 10, 25, 50, or 100 MPa using
either an unlubricated or a lubricated die and stored individually at 35° C in sealed Mylar …
either an unlubricated or a lubricated die and stored individually at 35° C in sealed Mylar …
Understanding compression-induced amorphization of crystalline posaconazole
Process-induced phase transformations (PIPTs) of active pharmaceutical ingredients (APIs)
can alter APIs' physicochemical properties and impact performance of pharmaceutical drug …
can alter APIs' physicochemical properties and impact performance of pharmaceutical drug …