Cells measure a vast variety of signals, from their environment's stiffness to chemical
concentrations and gradients; physical principles strongly limit how accurately they can do …

G protein-coupled receptor (GPCR) signaling is the primary method eukaryotes use to
respond to specific cues in their environment. However, the relationship between stimulus …

The extracellular environment is a complex medium in which cells secrete and consume
metabolites. Molecular gradients are thereby created near cells, triggering various biological …

The pheromone response pathway of the yeast Saccharomyces cerevisiae is a well‐
established model for the study of G proteins and mitogen‐activated protein kinase (MAPK) …

Chemotaxis, a biased migration of cells under a chemical gradient, plays a significant role in
diverse biological phenomena including cancer metastasis. Stromal cells release signaling …

Directional chemosensing is ubiquitous in cell biology, but some cells such as mating yeast
paradoxically degrade the signal they aim to detect. While the data processing inequality …

When cells measure concentrations of chemical signals, they may average multiple
measurements over time in order to reduce noise in their measurements. However, when …

Chemotaxis, a biased migration of cells under a chemical gradient, plays a significant role in
diverse biological phenomena including cancer metastasis. Stromal cells release signaling …