Accurate quantification in PET and SPECT requires correction for a number of physical
factors, such as photon attenuation, Compton scattering and random coincidences (in PET) …

In this paper, the authors review the field of resolution modeling in positron emission
tomography (PET) image reconstruction, also referred to as point‐spread‐function modeling …

Purpose: The aim of this work was the assessment of the physical performance of the new
hybrid PET/CT system: Discovery‐690. Methods: The Discovery‐690 combines a lutetium …

Accurate system modeling in tomographic image reconstruction has been shown to reduce
the spatial variance of resolution and improve quantitative accuracy. System modeling can …

PET is a medical imaging modality with proven clinical value for disease diagnosis and
treatment monitoring. The integration of PET and CT on modern scanners provides a …

Brain PET in small structures is challenged by low resolution inducing bias in the activity
measurements. Improved spatial resolution may be obtained by using dedicated …

In the early days of PET, the partial volume effect (PVE) was identified as a serious factor
affecting image quality and limiting the accuracy of quantitative analysis. Because of the …

We developed a prototype small-animal PET scanner based on depth-encoding detectors
using dual-ended readout of small scintillator elements to produce high and uniform spatial …

Positron emission tomography (PET) is used extensively in clinical oncology for tumor
detection, staging and therapy response assessment. Quantitative measurements of tumor …

Our aim is to help put nuclear medicine at the forefront of quantitation on the path to the
realization of personalized medicine. We propose and evaluate (Part I) advanced image …