[HTML][HTML] mRNA vaccine development for emerging animal and zoonotic diseases

T Le, C Sun, J Chang, G Zhang, X Yin - Viruses, 2022 - mdpi.com
In the prevention and treatment of infectious diseases, mRNA vaccines hold great promise
because of their low risk of insertional mutagenesis, high potency, accelerated development …

[HTML][HTML] Immune escape mechanism and vaccine research progress of African swine fever virus

Z Wang, Q Ai, S Huang, Y Ou, Y Gao, T Tong, H Fan - Vaccines, 2022 - mdpi.com
African swine fever virus (ASFV) is the causative agent of the epidemic of African swine fever
(ASF), with virulent strains having a mortality rate of up to 100% and presenting devastating …

[HTML][HTML] I226R protein of African swine fever virus is a suppressor of innate antiviral responses

J Hong, X Chi, X Yuan, F Wen, KR Rai, L Wu, Z Song… - Viruses, 2022 - mdpi.com
African swine fever is one of the most devastating swine diseases caused by African swine
fever virus (ASFV). Although ASFV encodes more than 160 viral proteins, the implication of a …

[HTML][HTML] M448R and MGF505-7R: Two African swine fever virus antigens commonly recognized by ASFV-specific T-cells and with protective potential

L Bosch-Camós, E López, J Collado, MJ Navas… - Vaccines, 2021 - mdpi.com
African swine fever (ASF) is today′ s number one threat for the global swine industry.
Neither commercial vaccine nor treatment is available against ASF and, thus far, only live …

[HTML][HTML] Adaptive cellular immunity against African swine fever virus infections

A Schäfer, G Franzoni, CL Netherton, L Hartmann… - Pathogens, 2022 - mdpi.com
African swine fever virus (ASFV) remains a threat to global pig populations. Infections with
ASFV lead to a hemorrhagic disease with up to 100% lethality in Eurasian domestic and wild …

[HTML][HTML] Adenovirus-vectored African swine fever virus pp220 induces robust antibody, IFN-γ, and CTL responses in pigs

MD Zajac, N Sangewar, S Lokhandwala… - Frontiers in Veterinary …, 2022 - frontiersin.org
African Swine Fever Virus (ASFV) poses a serious threat to the pork industry worldwide;
however, there is no safe vaccine or treatment available. The development of an efficacious …

[HTML][HTML] Feeding Spray-Dried Porcine Plasma to Pigs Improves the Protection Afforded by the African Swine Fever Virus (ASFV) BA71∆ CD2 Vaccine Prototype …

J Pujols, E Blázquez, J Segalés, F Rodríguez… - Vaccines, 2023 - mdpi.com
This study aimed to evaluate the effects of feeding spray-dried porcine plasma (SDPP) on
the protection afforded by the BA71∆ CD2 African swine fever virus (ASFV) vaccine …

[HTML][HTML] Efficient detection of African Swine Fever Virus using minimal equipment through a LAMP PCR method

JA Bohorquez, S Lanka, R Rosell… - Frontiers in cellular …, 2023 - frontiersin.org
African swine fever virus (ASFV) currently represents the biggest threat to the porcine
industry worldwide, with high economic impact and severe animal health and welfare …

[HTML][HTML] Transcriptome profile of spleen tissues from locally-adapted Kenyan pigs (Sus scrofa) experimentally infected with three varying doses of a highly virulent …

EM Machuka, J Juma, AWT Muigai, JO Amimo, R Pelle… - BMC genomics, 2022 - Springer
Background African swine fever (ASF) is a lethal hemorrhagic disease affecting domestic
pigs resulting in up to 100% mortality rates caused by the ASF virus (ASFV). The locally …

[HTML][HTML] Bridging the Gap: Can COVID-19 Research Help Combat African Swine Fever?

D Pakotiprapha, S Kuhaudomlarp, R Tinikul… - Viruses, 2023 - mdpi.com
African swine fever (ASF) is a highly contagious and economically devastating disease
affecting domestic pigs and wild boar, caused by African swine fever virus (ASFV). Despite …