Recent research efforts focusing on the many mechanisms participating in the resolution of
acute inflammation have uncovered a new genus of pro-resolving lipid mediators. These …

Herein we report the first total synthesis of RvD2n‐3 DPA, an endogenously formed
mediator biosynthesized from the omega‐3 fatty acid n‐3 docosapentaenoic acid. The key …

Polyunsaturated fatty acids and their metabolites have been reported in which their pathway
has potential for the modulation of cancer cell growth. 13-(S)-HODE and 15-(S)-HETE, both …

We studied the synthesis of RvD1, a pro-resolving mediator. The intermediate containing vic-
diol and enal functional groups was prepared via the oxidation of the γ, δ-epoxy alcohol …

Methoxylated ether lipids (MELs) are a subset of 1-O-alkyl-sn-glycerols that are found
ubiquitously in nature in very low concentrations. The MELs occur in significantly higher …

Two trans-enynyl alcohol intermediates corresponding to the C1–C8 and C13–C22 parts of
resolvin D6 (RvD6) were prepared through the Hudrlik–Peterson reaction of the TMS …

As an extension of the study on the Hudrlik–Peterson reaction of trans-TMS-epoxy alcohols
with lithium acetylides, four cis-TMS-epoxy alcohols possessing different alkyl substituents …

Abstract ω-3 Fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid
(DHA) produce hydroxylated metabolites that mediate anti-inflammatory and pro-resolving …