[HTML][HTML] Systemic autoinflammatory diseases

J Krainer, S Siebenhandl, A Weinhäusel - Journal of autoimmunity, 2020 - Elsevier
Systemic autoinflammatory diseases (SAIDs) are a growing group of disorders caused by a
dysregulation of the innate immune system leading to episodes of systemic inflammation. In …

[HTML][HTML] Presentation of a new mutation in FMF and evaluating the frequency of distribution of the MEFV gene mutation in our region with clinical findings

A Arpacı, S Doğan, HF Erdoğan, Ç El… - Molecular Biology Reports, 2021 - Springer
Abstract Familial Mediterranean Fever (FMF), which is an autosomal recessive disease
characterized by recurrent self-limiting fever, peritonitis, pleuritis, arthritis and erysipelas-like …

Anakinra for colchicine refractory familial Mediterranean fever: a cohort of 44 patients

L Marko, A Shemer, M Lidar, C Grossman… - …, 2021 - academic.oup.com
Objective FMF is an autoinflammatory disease of genetic origin. Colchicine is the mainstay
of treatment for the prevention of attacks and long-term complications but 5–10% of FMF …

Genotype–phenotype associations in familial mediterranean fever: A study of 500 Egyptian pediatric patients

AE Beshlawy, AER Zekri, MS Ramadan… - Clinical …, 2022 - Springer
Abstract Introduction Familial Mediterranean fever (FMF) is the most prevalent monogenic
autoinflammatory disease, caused by recessively inherited MEFV gene mutations. The most …

NLRP13 inflammasome complex is hypermethylated in familial Mediterranean fever and global methylation correlates with the disease severity

FY Caldiran, K Deveci, E Cacan - Annals of Human Genetics, 2023 - Wiley Online Library
Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by variations in
the MEFV gene, which encodes the pyrin protein, a member of the inflammasomes. Despite …

A mathematical model of Familial Mediterranean Fever predicts mechanisms controlling inflammation

M Veyssiere, SS Aghamiri, AH Cervantes, T Henry… - Clinical …, 2023 - Elsevier
Abstract Background Familial Mediterranean Fever (FMF) is a monogenic disease caused
by gain-of-function mutations in the MEditerranean FeVer (MEFV) gene. The molecular …

Perinatal outcomes and long-term infectious morbidity of offspring born to mothers with familial Mediterranean fever

I Asher, E Sheiner, NT Willner, L Zeller… - Archives of Gynecology …, 2023 - Springer
Purpose To investigate perinatal outcomes and long-term infectious morbidity in children of
mothers with familial Mediterranean fever (FMF). Methods A population-based cohort study …

Genetic and clinical features of familial mediterranean fever (FMF) in a homogeneous cohort of patients from South-Eastern Italy

A Di Ciaula, M Iacoviello, L Bonfrate, M Khalil… - European Journal of …, 2023 - Elsevier
Abstract Familial Mediterranean Fever (FMF) is linked with the MEFV gene and is the
commonest among monogenic autoinflammatory diseases, with high prevalence in the …

Epigenetics and familial mediterranean fever

R Lotfy, O Ali, W Zarouk, H EL-Bassyouni… - … and Medical Sciences, 2021 - journals.ekb.eg
Throughout the last 20 years, the concept of auto-inflammation is developed, culminating
with the finding of how gene mutations of Mediterranean Fever (MEFV) seemed to be …

[HTML][HTML] Familial Mediterranean fever in Chinese children: a case series

J Li, W Wang, L Zhong, J Pan, Z Yu, S Jian… - Frontiers in …, 2019 - frontiersin.org
Background: Familial Mediterranean fever (FMF) is an inherited auto-inflammatory disorder
and is extremely rare in Chinese. This study aimed to investigate the demographic, clinical …