From conventional to precision therapy in canine mammary cancer: a comprehensive review

G Valdivia, Á Alonso-Diez, D Pérez-Alenza… - Frontiers in veterinary …, 2021 - frontiersin.org
Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …

Oncolytic adenovirus: prospects for cancer immunotherapy

Y Zhao, Z Liu, L Li, J Wu, H Zhang, H Zhang… - Frontiers in …, 2021 - frontiersin.org
Immunotherapy has moved to the forefront of modern oncologic treatment in the past few
decades. Various forms of immunotherapy currently are emerging, including oncolytic …

[HTML][HTML] Targeting PD-1/PD-L1 in cancer immunotherapy: an effective strategy for treatment of triple-negative breast cancer (TNBC) patients

S Kumar, M Chatterjee, P Ghosh, KK Ganguly, M Basu… - Genes & …, 2023 - Elsevier
Maintaining the balance between eliciting immune responses against foreign proteins and
tolerating self-proteins is crucial for maintenance of homeostasis. The functions of …

Research progress on immunotherapy in triple‑negative breast cancer

X Zhang, X Ge, T Jiang, R Yang… - … Journal of Oncology, 2022 - spandidos-publications.com
Triple‑negative breast cancer (TNBC) is a highly heterogeneous and aggressive
malignancy. Due to the absence of estrogen receptors and progesterone receptors and the …

Oncolytic viruses for triple negative breast cancer and beyond

S Jin, Q Wang, H Wu, D Pang, S Xu - Biomarker Research, 2021 - Springer
Biological therapy is considered an alternative treatment capable of eliciting the same
effects on tumors as surgery, radiotherapy, and chemotherapy. As a major player in …

Therapeutic efficacy of oncolytic viruses in fighting cancer: Recent advances and perspective

GA Garmaroudi, F Karimi, LG Naeini… - Oxidative Medicine …, 2022 - Wiley Online Library
Immunotherapy is at the cutting edge of modern cancer treatment. Innovative medicines
have been developed with varying degrees of success that target all aspects of tumor …

Clinical trials of oncolytic viruses in breast cancer

ME Carter, A Koch, UM Lauer, AD Hartkopf - Frontiers in oncology, 2021 - frontiersin.org
Breast cancer is the second most common kind of cancer worldwide and oncolytic viruses
may offer a new treatment approach. There are three different types of oncolytic viruses used …

Optimizing oncolytic viral design to enhance antitumor efficacy: progress and challenges

S Chaurasiya, Y Fong, SG Warner - Cancers, 2020 - mdpi.com
The field of oncolytic virotherapy has seen remarkable advancements in last two decades,
leading to approval of the first oncolytic immuno-virotherapy, Talimogene Laherparepvec, for …

Comprehensive assessment on the applications of oncolytic viruses for cancer immunotherapy

RK Omole, O Oluwatola, MT Akere, J Eniafe… - Frontiers in …, 2022 - frontiersin.org
The worldwide burden of cancers is increasing at a very high rate, including the aggressive
and resistant forms of cancers. Certain levels of breakthrough have been achieved with the …

Recombinant orthopoxvirus primes colon cancer for checkpoint inhibitor and cross-primes T cells for antitumor and antiviral immunity

SI Kim, AK Park, S Chaurasiya, S Kang, J Lu… - Molecular cancer …, 2021 - AACR
Although it is known that oncolytic viruses can inflame and recruit immune cells to otherwise
immunosuppressed tumor microenvironments, the influence of the antiviral immune …