Sepsis is a systemic inflammatory disease caused by severe infections that involves multiple
systemic organs, among which the lung is the most susceptible, leaving patients highly …

SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2), an RNA-containing virus
belonging to the Coronaviridae family, is a causative agent of COVID-19 (from CoronaVirus …

Background Regarding the global coronavirus disease 2019 (COVID)-19 pandemic, kidney
clear cell carcinoma (KIRC) has acquired a higher infection probability and may induce fatal …

Sepsis-induced neuroinflammation is significantly associated with sepsis-related brain
dysfunction. Remimazolam is a novel ultra-short-acting benzodiazepine anesthetic with …

Objective Oxygen and hemodynamic management are important for providing a sufficient
adequate oxygen-containing blood to the organs for septic patients. In present study, we …

Background: ACT001 is a potent anti-inflammatory small-molecule drug. However, the
single cell and spatial molecular basis of pyroptosis and whether ACT001 exerts a …

The importance of telomeres as special structures at the ends of chromosomes is gradually
gaining prominence. They are composed of short, multi-repeated non-transcribed …

Methods This study included 50 patients with COVID-19 pneumonia who received oxygen
therapy using a reservoir mask at≥ 15 L/m, high-flow oxygen therapy at 60 L/m, or oxygen …

Supraphysiological concentrations of oxygen (hyperoxia) can compromise host defense and
increase susceptibility to bacterial and viral infections, causing ventilator-associated …

Advanced age significantly influences outcomes in acute respiratory distress syndrome, with
implications for intensive care unit-free days, ventilator-free days, and mortality …