[HTML][HTML] Childhood maltreatment and DNA methylation: A systematic review

CAM Cecil, Y Zhang, T Nolte - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
DNA methylation (DNAm)–an epigenetic process that regulates gene expression–may
represent a mechanism for the biological embedding of early traumatic experiences …

Research Review: Psychological and psychosocial treatments for children and young people with post‐traumatic stress disorder: a network meta‐analysis

I Mavranezouli, O Megnin‐Viggars… - Journal of child …, 2020 - Wiley Online Library
Background Post‐traumatic stress disorder (PTSD) is a potentially chronic and disabling
disorder that affects a significant minority of youth exposed to trauma. Previous studies have …

DunedinPACE, a DNA methylation biomarker of the pace of aging

DW Belsky, A Caspi, DL Corcoran, K Sugden… - Elife, 2022 - elifesciences.org
Background: Measures to quantify changes in the pace of biological aging in response to
intervention are needed to evaluate geroprotective interventions for humans. Previously, we …

Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm

DW Belsky, A Caspi, L Arseneault, A Baccarelli… - Elife, 2020 - elifesciences.org
Biological aging is the gradual, progressive decline in system integrity that occurs with
advancing chronological age, causing morbidity and disability. Measurements of the pace of …

[HTML][HTML] Measuring childhood maltreatment to predict early-adult psychopathology: Comparison of prospective informant-reports and retrospective self-reports

JB Newbury, L Arseneault, TE Moffitt, A Caspi… - Journal of psychiatric …, 2018 - Elsevier
Both prospective informant-reports and retrospective self-reports may be used to measure
childhood maltreatment, though both methods entail potential limitations such as …

[HTML][HTML] Exploration of NO2 and PM2. 5 air pollution and mental health problems using high-resolution data in London-based children from a UK longitudinal cohort …

S Roberts, L Arseneault, B Barratt, S Beevers… - Psychiatry …, 2019 - Elsevier
Air pollution is a worldwide environmental health issue. Increasingly, reports suggest that
poor air quality may be associated with mental health problems, but these studies often use …

[HTML][HTML] The long‐term impact of bullying victimization on mental health

L Arseneault - World psychiatry, 2017 - ncbi.nlm.nih.gov
There is little doubt today that being bullied in childhood is an adverse experience that casts
a shadow on children's and adolescents' mental health and wellbeing. After several …

Adolescent victimization and early-adult psychopathology: approaching causal inference using a longitudinal twin study to rule out noncausal explanations

JD Schaefer, TE Moffitt, L Arseneault… - Clinical …, 2018 - journals.sagepub.com
Adolescence is the peak age for both victimization and mental disorder onset. Previous
research has reported associations between victimization exposure and many psychiatric …

Gene–environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach

V Warrier, ASF Kwong, M Luo, S Dalvie, J Croft… - The Lancet …, 2021 - thelancet.com
Background Childhood maltreatment is associated with poor mental and physical health.
However, the mechanisms of gene–environment correlations and the potential causal …

The origins of cognitive deficits in victimized children: implications for neuroscientists and clinicians

A Danese, TE Moffitt, L Arseneault… - American journal of …, 2017 - Am Psychiatric Assoc
Objective: Individuals reporting a history of childhood violence victimization have impaired
brain function. However, the clinical significance, reproducibility, and causality of these …