Acoustofluidic separation of cells and particles
Acoustofluidics, the integration of acoustics and microfluidics, is a rapidly growing research
field that is addressing challenges in biology, medicine, chemistry, engineering, and …
field that is addressing challenges in biology, medicine, chemistry, engineering, and …
Circulating tumor cell isolation, culture, and downstream molecular analysis
S Sharma, R Zhuang, M Long, M Pavlovic, Y Kang… - Biotechnology …, 2018 - Elsevier
Circulating tumor cells (CTCs) are a major contributor of cancer metastases and hold a
promising prognostic significance in cancer detection. Performing functional and molecular …
promising prognostic significance in cancer detection. Performing functional and molecular …
Iso-acoustic focusing of cells for size-insensitive acousto-mechanical phenotyping
Mechanical phenotyping of single cells is an emerging tool for cell classification, enabling
assessment of effective parameters relating to cells' interior molecular content and structure …
assessment of effective parameters relating to cells' interior molecular content and structure …
Microfluidic droplet handling by bulk acoustic wave (BAW) acoustophoresis
Droplet microfluidics has emerged as a prospering field for lab-on-a-chip devices, where
droplets serve as liquid vessels eg for biochemical reagents. Key to the fluid processing in …
droplets serve as liquid vessels eg for biochemical reagents. Key to the fluid processing in …
Acoustofluidic, label-free separation and simultaneous concentration of rare tumor cells from white blood cells
Enrichment of rare cells from peripheral blood has emerged as a means to enable
noninvasive diagnostics and development of personalized drugs, commonly associated with …
noninvasive diagnostics and development of personalized drugs, commonly associated with …
High-throughput acoustic separation of platelets from whole blood
Platelets contain growth factors which are important in biomedical and clinical applications.
In this work, we present an acoustic separation device for high-throughput, non-invasive …
In this work, we present an acoustic separation device for high-throughput, non-invasive …
Acoustic impedance matched buffers enable separation of bacteria from blood cells at high cell concentrations
Sepsis is a common and often deadly systemic response to an infection, usually caused by
bacteria. The gold standard for finding the causing pathogen in a blood sample is blood …
bacteria. The gold standard for finding the causing pathogen in a blood sample is blood …
Acoustic separation in plastic microfluidics for rapid detection of bacteria in blood using engineered bacteriophage
A more effective treatment of bacteremia requires a diagnostic platform that is both sensitive,
accurate and rapid. Currently, clinical laboratory techniques require growth of bacteria prior …
accurate and rapid. Currently, clinical laboratory techniques require growth of bacteria prior …
A single inlet two-stage acoustophoresis chip enabling tumor cell enrichment from white blood cells
Metastatic disease is responsible for most cancer deaths, and hematogenous spread
through circulating tumor cells (CTC) is a prerequisite for tumor dissemination. CTCs may …
through circulating tumor cells (CTC) is a prerequisite for tumor dissemination. CTCs may …
Acoustic force density acting on inhomogeneous fluids in acoustic fields
We present a theory for the acoustic force density acting on inhomogeneous fluids in
acoustic fields on time scales that are slow compared to the acoustic oscillation period. The …
acoustic fields on time scales that are slow compared to the acoustic oscillation period. The …