NMR characterization of the dynamics of biomacromolecules
AG Palmer III - Chemical reviews, 2004 - ACS Publications
Function in biological systems is exquisitely dependent on spatial and temporal changes in
biomacromolecules. Innumerable biological processes ultimately rely on transduction of …
biomacromolecules. Innumerable biological processes ultimately rely on transduction of …
Fast time scale dynamics of protein backbones: NMR relaxation methods, applications, and functional consequences
VA Jarymowycz, MJ Stone - Chemical reviews, 2006 - ACS Publications
Over the past 15 years there has been an explosion of research on the dynamical properties
of proteins, largely driven by the emergence of a handful of techniques that are sensitive to …
of proteins, largely driven by the emergence of a handful of techniques that are sensitive to …
A hierarchy of timescales in protein dynamics is linked to enzyme catalysis
KA Henzler-Wildman, M Lei, V Thai, SJ Kerns… - Nature, 2007 - nature.com
The synergy between structure and dynamics is essential to the function of biological
macromolecules. Thermally driven dynamics on different timescales have been …
macromolecules. Thermally driven dynamics on different timescales have been …
Large amplitude conformational change in proteins explored with a plastic network model: adenylate kinase
P Maragakis, M Karplus - Journal of Molecular Biology, 2005 - Elsevier
The plastic network model (PNM) is used to generate a conformational change pathway for
Escherichia coli adenylate kinase based on two crystal structures, namely that of an open …
Escherichia coli adenylate kinase based on two crystal structures, namely that of an open …
Minimum free energy path of ligand-induced transition in adenylate kinase
Y Matsunaga, H Fujisaki, T Terada… - PLoS computational …, 2012 - journals.plos.org
Large-scale conformational changes in proteins involve barrier-crossing transitions on the
complex free energy surfaces of high-dimensional space. Such rare events cannot be …
complex free energy surfaces of high-dimensional space. Such rare events cannot be …
New approaches to the dynamic interpretation and prediction of NMR relaxation data from proteins
R Brüschweiler - Current opinion in structural biology, 2003 - Elsevier
NMR relaxation experiments of isotopically labeled proteins provide a wealth of information
on reorientational global and local dynamics on nanosecond and subnanosecond …
on reorientational global and local dynamics on nanosecond and subnanosecond …
The physical basis of model-free analysis of NMR relaxation data from proteins and complex fluids
B Halle - The Journal of chemical physics, 2009 - pubs.aip.org
NMR relaxation experiments have provided a wealth of information about molecular motions
in macromolecules and ordered fluids. Even though a rigorous theory of spin relaxation is …
in macromolecules and ordered fluids. Even though a rigorous theory of spin relaxation is …
Structural dynamics of bio-macromolecules by NMR: The slowly relaxing local structure approach
E Meirovitch, YE Shapiro, A Polimeno… - Progress in nuclear …, 2010 - Elsevier
Protein dynamics by NMR has been reviewed extensively in recent years [1–10]. These
surveys show decisively that information on structure should be complemented by …
surveys show decisively that information on structure should be complemented by …
Interdomain mobility in di‐ubiquitin revealed by NMR
Abstract Domain orientation and dynamics can play an essential role in the function of
multidomain proteins. Lys48‐linked polyubiquitin chains, the principal signal for …
multidomain proteins. Lys48‐linked polyubiquitin chains, the principal signal for …
[HTML][HTML] Fokker-Planck formalism in magnetic resonance simulations
I Kuprov - Journal of magnetic resonance, 2016 - Elsevier
This paper presents an overview of the Fokker-Planck formalism for non-biological magnetic
resonance simulations, describes its existing applications and proposes some novel ones …
resonance simulations, describes its existing applications and proposes some novel ones …