Mesenchymal stem cells (MSC) are multipotent cells, functioning as precursors to a variety
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …

MSCs are nonhematopoietic stromal cells that are capable of differentiating into, and
contribute to the regeneration of, mesenchymal tissues such as bone, cartilage, muscle …

Microvascular reconstruction is the state-of-the-art in many fields of defect surgery today.
Currently, reconstruction of large bony defects involves harvesting of autologous bone …

Abstract Bone Morphogenetic Proteins (BMPs) are multifunctional secreted cytokines, which
belong to the TGF-β superfamily. These glycoproteins act as a disulfide-linked homo-or …

Mesenchymal stromal cells (MSCs) can be isolated from various tissues such as bone
marrow aspirates, fat or umbilical cord blood. These cells have the ability to proliferate in …

Aim: To determine whether fluid flow-induced shear stress affects the differentiation of bone
marrow-derived human mesenchymal stem cells (hMSCs) into osteogenic cells. Materials & …

PURPOSE: Large mandibular resection defects historically have been treated using
autogenous bone grafts and reconstruction plates. However, a major drawback of large …

Osteogenic differentiation of human mesenchymal stem cells (hMSCs) is classically thought
to be mediated by different cytokines such as the bone morphogenetic proteins (BMPs) …

The first non-hematopoietic mesenchymal stem cells (MSCs) were discovered by
Friedenstein in 1976, who described clonal, plastic adherent cells from bone marrow …

Bone marrow‐derived mesenchymal stem cells (MSC) are multipotent, self‐renewing,
mesodermal‐origin stem cells that are sequestered in the endosteal compartment. MSC are …