Biomedical applications of multifunctional polymeric nanocarriers: a review of current literature

A Karabasz, M Bzowska… - International Journal of …, 2020 - Taylor & Francis
Polymeric nanomaterials have become a prominent area of research in the field of drug
delivery. Their application in nanomedicine can improve bioavailability, pharmacokinetics …

Review on Experimental Treatment Strategies Against Trypanosoma cruzi

AL Mazzeti, P Capelari-Oliveira, MT Bahia… - Journal of …, 2021 - Taylor & Francis
Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Currently, only nitroheterocyclic nifurtimox (NFX) and benznidazole (BNZ) are …

PEGylated and functionalized polylactide-based nanocapsules: An overview

MA de Oliveira, RS Araújo, VCF Mosqueira - International Journal of …, 2023 - Elsevier
Polymeric nanocapsules (NC) are versatile mixed vesicular nanocarriers, generally
containing a lipid core with a polymeric wall. They have been first developed over four …

Nanomaterials as ultrasound theragnostic tools for heart disease treatment/diagnosis

E Alphandéry - International Journal of Molecular Sciences, 2022 - mdpi.com
A variety of different nanomaterials (NMs) such as microbubbles (MBs), nanobubbles (NBs),
nanodroplets (NDs), and silica hollow meso-structures have been tested as ultrasound …

Drug delivery systems based on nonimmunogenic biopolymers

MC García - Engineering of Biomaterials for Drug Delivery Systems, 2018 - Elsevier
Biopolymers have attracted considerable interest for the development of drug delivery
systems (DDSs) owing to their biocompatibility, nontoxicity, renewability, and mild …

Mechanisms of interaction of biodegradable polyester nanocapsules with non-phagocytic cells

IC Trindade, G Pound-Lana, DGS Pereira… - European Journal of …, 2018 - Elsevier
The interaction of polymer nanocapsules (NC) prepared from four biodegradable polyesters
with variable polymer hydrophobicity (PCL, PLA, PLGA and PLA-PEG) was investigated in …

Theracurmin Modulates Cardiac Inflammation in Experimental Model of Trypanosoma cruzi Infection

V Louise, BAA Machado, WM Pontes… - Tropical Medicine and …, 2023 - mdpi.com
Theracurmin is a nanoparticle formulation derived from curcumin, a bioactive compound
known for its antioxidant and anti-inflammatory properties. Trypanosoma cruzi, the …

Use of Nanocarriers Containing Antitrypanosomal Drugs for the Treatment of Chagas Disease

DF Paiva, APS Matos, DA Garófalo, T do Nascimento… - Pharmaceuticals, 2023 - mdpi.com
Chagas disease, caused by the Trypanosoma cruzi parasitic protozoan, is a neglected
tropical disease (NTD) of significant incidence in Latin America. Transmission to humans …

Nano-medicines a hope for Chagas disease!

SD Choudhury - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Chagas disease, is a vector-mediated tropical disease whose causative agent is a parasitic
protozoan named Trypanosoma cruzi. It is a very severe health issue in South America and …

[HTML][HTML] pH-sensitive doxorubicin-tocopherol succinate prodrug encapsulated in docosahexaenoic acid-based nanostructured lipid carriers: An effective strategy to …

EB Lages, RS Fernandes, MMS Andrade… - Biomedicine & …, 2021 - Elsevier
Side effects often limit the use of doxorubicin (DOX) in cancer treatment. We have recently
developed a nanostructured lipid carrier (NLC) formulation for synergistic chemotherapy …