Enhancing the drug discovery process: Bayesian inference for the analysis and comparison of dose–response experiments

C Labelle, A Marinier, S Lemieux - Bioinformatics, 2019 - academic.oup.com
Motivation The efficacy of a chemical compound is often tested through dose–response
experiments from which efficacy metrics, such as the IC 50, can be derived. The Marquardt …

Estimate the median lethal dose of a biological experiment with modified Weibull model

NH Al-Noor, IH Hussein, SA Jasim - AIP Conference Proceedings, 2023 - pubs.aip.org
The main objective of this paper is to construct a model for the relationship of response with
dose and time by using the modified Weibull model as a statistical model for response times …

Développement d'un processus d'analyse d'expériences dose-réponse par inférence Bayésienne et application à de larges jeux de données

C Labelle - 2024 - papyrus.bib.umontreal.ca
Dans le contexte du processus de découverte de médicaments, divers composés chimiques
sont développés, testés et optimisés dans l'optique d'identifier de nouvelles thérapies …

Methods to Incorporate Global Information in Local Models to Offset Sample Size Constraints

RA Kesawan - 2022 - search.proquest.com
The application of local models has proven to be successful in many areas. The localmodels
allow flexible modeling of an otherwise heterogeneous population by identifyingpockets of …

[PDF][PDF] Bayesian Analysis to Improve the Interpretation of Radiobiology Data

K Jeleń, L Grzanka - researchgate.net
Bayesian Analysis to Improve the Interpretation of Radiobiology Data Page 1 Bayesian
Analysis to Improve the Interpretation of Radiobiology Data Kinga Jeleń, Leszek Grzanka …