Genotype× environment interactions in gene regulation and complex traits

C Boye, S Nirmalan, A Ranjbaran, F Luca - Nature Genetics, 2024 - nature.com
Genotype× environment interactions (GxE) have long been recognized as a key mechanism
underlying human phenotypic variation. Technological developments over the past 15 years …

[HTML][HTML] Early-life exposure to perfluoroalkyl substances and serum antibody concentrations towards common childhood vaccines in 18-month-old children in the …

A Sigvaldsen, FD Højsager, HM Paarup, IH Beck… - Environmental …, 2024 - Elsevier
Exposure to per-and polyfluoroalkyl substances (PFAS) has been associated with reduced
antibody response to childhood vaccinations. Previous studies have mostly focused on …

[HTML][HTML] Determinants of per-and polyfluoroalkyl substances (PFAS) exposure among Wisconsin residents

R Pomazal, K Malecki, N Stanton, B Shelton… - Environmental …, 2024 - Elsevier
Background Per-and polyfluoroalkyl substances (PFAS) include thousands of manufactured
compounds with growing public health concerns due to their potential for widespread …

Exposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis

A Hari, MDM AbdulHameed, MR Balik-Meisner… - Frontiers in …, 2024 - frontiersin.org
Toxicants with the potential to bioaccumulate in humans and animals have long been a
cause for concern, particularly due to their association with multiple diseases and organ …

Exposure to perfluorinated alkyl substances and health effects in pregnant women and their children

M Ebel - 2024 - portal.research.lu.se
Per-and polyfluorinated alkyl substances (PFAS) are chemicals that have gained attention
during the last years. There are about 10,000 different PFAS compounds, and due to their …

Application of New Approach Methodologies in Per-and Polyfluoroalkyl Substances (PFAS).

G Qingrong, W Jianshe - Asian Journals of Ecotoxicology, 2024 - search.ebscohost.com
Before the 21st Century, plenty of laboratory animals were applied to assess the toxicity and
potential health risks of compounds. However, with the growing production and application …

Per and Polyfluoroalkyl Substances and Emerging Toxicity Mechanisms: Alterations in Liver-Derived Extracellular Vesicle Content, Regulation, and Function.

C Carberry - 2024 - cdr.lib.unc.edu
Exposure to per and polyfluoroalkyl substances (PFAS) represent a global public health
concern, with associated health effects spanning across diverse biological systems. Overall …