Zirconium Hydride Catalysis Initiated by Tetrabutylammonium Fluoride

AN Aloiau, BM Bobek, KE Pearson… - The Journal of …, 2024 - ACS Publications
In our drug discovery campaigns to target the oncogenic drivers of cancers, the demand for
a chemoselective, stereoselective and economical synthesis of chiral benzylamines drove …

Zirconium Hydride Catalysis Initiated by Tetrabutylammonium Fluoride

S Harwood, A Aloiau, B Bobek, K Pearson, K Cherry… - 2024 - chemrxiv.org
In our drug discovery campaigns to target the oncogenic drivers of cancers, the demand for
a chemoselective, stereoselective and economical synthesis of chiral benzylamines drove …

Benzopyrimidin-4 (3H)-ones as PI3K inhibitors

JF Blake, ML Boys, DA MARKESKA, JN PAYETTE… - 2023 - Google Patents
AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O ([C@ H] 1C
[C@@](O)(CC= 2C (O)= C3C (= O) C= 4C= CC= C (C= 4C (= O) C3= C (O) C= 21) OC) C …

Allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) for the treatment of disease

EA Kesicki, ER Hickey - US Patent 12,030,862, 2024 - Google Patents
US12030862B2 - Allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) for the
treatment of disease - Google Patents US12030862B2 - Allosteric chromenone inhibitors of …

Allosteric chromenone inhibitors of phosphoinositide 3-kinase (pi3k) for the treatment of disease

ED Anderson, SD Aronow, NA Boyles… - US Patent App. 18 …, 2023 - Google Patents
2023-04-19 Assigned to LOXO ONCOLOGY, INC. reassignment LOXO ONCOLOGY, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

[引用][C] RECENT ADVANCES IN SELECTIVELY TARGETING PI3Kα

DJ St. Jean Jr, T Tieu, A Guzman-Perez… - 2024 Medicinal …, 2024 - ACS Publications