Biliary atresia and other cholestatic childhood diseases: advances and future challenges
HJ Verkade, JA Bezerra, M Davenport… - Journal of …, 2016 - Elsevier
Biliary Atresia and other cholestatic childhood diseases are rare conditions affecting the
function and/or anatomy along the canalicular-bile duct continuum, characterised by onset of …
function and/or anatomy along the canalicular-bile duct continuum, characterised by onset of …
[HTML][HTML] Vitamin K deficiency bleeding in infancy
S Araki, A Shirahata - Nutrients, 2020 - mdpi.com
Vitamin K is essential for the synthesis of few coagulation factors. Infants can easily develop
vitamin K deficiency owing to poor placental transfer, low vitamin K content in breast milk …
vitamin K deficiency owing to poor placental transfer, low vitamin K content in breast milk …
Identification of a plant isoflavonoid that causes biliary atresia
K Lorent, W Gong, KA Koo… - Science translational …, 2015 - science.org
Biliary atresia (BA) is a rapidly progressive and destructive fibrotic disorder of unknown
etiology affecting the extrahepatic biliary tree of neonates. Epidemiological studies suggest …
etiology affecting the extrahepatic biliary tree of neonates. Epidemiological studies suggest …
[HTML][HTML] Knockdown of long noncoding RNA SAN rejuvenates aged adipose-derived stem cells via miR-143-3p/ADD3 axis
H Xiong, S Ren, J Chen, X Yang, Y Liu, Z Xu… - Stem Cell Research & …, 2023 - Springer
Background Senescent adipose-derived stem cells (ASCs) exhibit reduced therapeutic
efficacy during wound healing. Transcriptional regulation factors including long noncoding …
efficacy during wound healing. Transcriptional regulation factors including long noncoding …
[HTML][HTML] Identification of a wide spectrum of ciliary gene mutations in nonsyndromic biliary atresia patients implicates ciliary dysfunction as a novel disease mechanism
Background Biliary atresia (BA) is the most common obstructive cholangiopathy in neonates,
often progressing to end-stage cirrhosis. BA pathogenesis is believed to be multifactorial …
often progressing to end-stage cirrhosis. BA pathogenesis is believed to be multifactorial …
Biliary atresia as a disease starting in utero: implications for treatment, diagnosis, and pathogenesis
KR Mysore, BL Shneider… - Journal of pediatric …, 2019 - journals.lww.com
Biliary atresia (BA) is the most common reason for pediatric liver transplant. BA's varied
presentation, natural history, and treatment with the Kasai portoenterostomy have been well …
presentation, natural history, and treatment with the Kasai portoenterostomy have been well …
Advances in paediatric gastroenterology
PKH Tam, PHY Chung, SD St Peter, CP Gayer… - The Lancet, 2017 - thelancet.com
Recent developments in paediatric gastrointestinal surgery have focused on minimally
invasive surgery, the accumulation of high-quality clinical evidence, and scientific research …
invasive surgery, the accumulation of high-quality clinical evidence, and scientific research …
Biliary atresia: east versus west
PHY Chung, S Zheng, PKH Tam - Seminars in Pediatric Surgery, 2020 - Elsevier
Biliary atresia (BA) is a common cause of surgical jaundice during the neonatal period. It is
currently considered as a spectrum of diseases with a common final pathology characterized …
currently considered as a spectrum of diseases with a common final pathology characterized …
[HTML][HTML] Biliary atresia is associated with polygenic susceptibility in ciliogenesis and planar polarity effector genes
Background & Aims Biliary atresia (BA) is poorly understood and leads to liver
transplantation (LT), with the requirement for and associated risks of lifelong …
transplantation (LT), with the requirement for and associated risks of lifelong …
Hirschsprung's disease: a bridge for science and surgery
PKH Tam - Journal of pediatric surgery, 2016 - Elsevier
Background/purpose Understanding the true nature of the disease provided the basis for
appropriate surgery for Hirschsprung's disease some 60 years ago. Nevertheless, surgical …
appropriate surgery for Hirschsprung's disease some 60 years ago. Nevertheless, surgical …