The discovery of antibiotics marked a golden age in the revolution of human medicine.
However, decades later, bacterial infections remain a global healthcare threat, and a return …

Antimicrobial peptides (AMPs), or host defence peptides, are short proteins in various life
forms. Here we discuss AMPs, which may become a promising substitute or adjuvant in …

The membrane is one of the key structural materials of biology at the cellular level.
Composed predominantly of a bilayer of lipids with embedded and bound proteins, it defines …

Because of their favorable properties as macromolecular drugs, antibodies are a very
successful therapeutic modality for interfering with disease-relevant targets in the …

Hypothesis: Most textbook models for antimicrobial peptides (AMP) mode of action are
focused on structural effects and pore formation in lipid membranes, while these …

Temporin is an antimicrobial peptide (AMP) family discovered in the skin secretion of ranid
frog that has become a promising alternative for conventional antibiotic therapy. Herein, a …

In a report by WHO (2014), it was stated that antimicrobial resistance is an arising challenge
that needs to be resolved. This resistance is a critical issue in terms of disease or infection …

Multidrug-resistant (MDR) pathogens have been a growing threat to human health over the
years. Antimicrobial peptides (AMPs) with broad-spectrum antibiotic activity, as a promising …

Using small angle X-ray and neutron scattering (SAXS/SANS) and detailed theoretical
modelling we have elucidated the structure of the antimicrobial peptide, indolicidin, and the …

Dispersions of cubic liquid crystalline phases, also known as cubosomes, have shown great
promise as delivery vehicles for a wide range of medicines. Due to their ordered structure …