Physiological limitations and opportunities in microbial metabolic engineering

J Montaño López, L Duran, JL Avalos - Nature Reviews Microbiology, 2022 - nature.com
Metabolic engineering can have a pivotal role in increasing the environmental sustainability
of the transportation and chemical manufacturing sectors. The field has already developed …

Yarrowia lipolytica Strains and Their Biotechnological Applications: How Natural Biodiversity and Metabolic Engineering Could Contribute to Cell Factories …

C Madzak - Journal of Fungi, 2021 - mdpi.com
Among non-conventional yeasts of industrial interest, the dimorphic oleaginous yeast
Yarrowia lipolytica appears as one of the most attractive for a large range of white …

Rhodosporidium toruloides - A potential red yeast chassis for lipids and beyond

Z Wen, S Zhang, CK Odoh, M Jin… - FEMS Yeast …, 2020 - academic.oup.com
The red yeast Rhodosporidium toruloides naturally produces microbial lipids and
carotenoids. In the past decade or so, many studies demonstrated R. toruloides as a …

[HTML][HTML] Synthetic biology tools for engineering Yarrowia lipolytica

M Larroudé, T Rossignol, JM Nicaud… - Biotechnology …, 2018 - Elsevier
The non-conventional oleaginous yeast Yarrowia lipolytica shows great industrial promise. It
naturally produces certain compounds of interest but can also artificially generate non-native …

Yarrowia lipolytica as an Alternative and Valuable Source of Nutritional and Bioactive Compounds for Humans

ME Jach, A Malm - Molecules, 2022 - mdpi.com
Yarrowia lipolytica, an oleagineous species of yeast, is a carrier of various important
nutrients. The biomass of this yeast is an extensive source of protein, exogenous amino …

Yarrowia lipolytica: more than an oleaginous workhorse

KK Miller, HS Alper - Applied Microbiology and Biotechnology, 2019 - Springer
Microbial production of fuels and chemicals offers a means by which sustainable product
manufacture can be achieved. In this regard, Yarrowia lipolytica is a unique microorganism …

Carotenoids and their biosynthesis in fungi

G Sandmann - Molecules, 2022 - mdpi.com
Carotenoids represent a class of pigmented terpenoids. They are distributed in all taxonomic
groups of fungi. Most of the fungal carotenoids differ in their chemical structures to those …

CRISPR-Cas12a/Cpf1-assisted precise, efficient and multiplexed genome-editing in Yarrowia lipolytica

Z Yang, H Edwards, P Xu - Metabolic engineering communications, 2020 - Elsevier
CRISPR-Cas9 has been widely adopted as the basic toolkit for precise genome-editing and
engineering in various organisms. Alternative to Cas9, Cas12 or Cpf1 uses a simple crRNA …

Metabolic engineering of Yarrowia lipolytica for terpenoids production: advances and perspectives

G Zhang, H Wang, Z Zhang, KJ Verstrepen… - Critical Reviews in …, 2022 - Taylor & Francis
Terpenoids are a large family of natural products with diversified structures and functions
that are widely used in the food, pharmaceutical, cosmetic, and agricultural fields. However …

Lignocellulosic biomass as a substrate for oleaginous microorganisms: a review

G Valdés, RT Mendonça, G Aggelis - Applied Sciences, 2020 - mdpi.com
Microorganisms capable of accumulating lipids in high percentages, known as oleaginous
microorganisms, have been widely studied as an alternative for producing oleochemicals …