Rediscovering the therapeutic potential of agarwood in the management of chronic inflammatory diseases

JMR Alamil, KR Paudel, Y Chan, D Xenaki… - Molecules, 2022 - mdpi.com
The inflammatory response is a central aspect of the human immune system that acts as a
defense mechanism to protect the body against infections and injuries. A dysregulated …

New Azaphilones from the Marine-Derived Fungus Penicillium sclerotiorum E23Y-1A with Their Anti-Inflammatory and Antitumor Activities

Y Zeng, Z Wang, W Chang, W Zhao, H Wang, H Chen… - Marine Drugs, 2023 - mdpi.com
Nine new azaphilones, including penicilazaphilones I–N (1, 2 and 6–9), epi-geumsanol D
(3) and penidioxolanes C (4) and D (5) were isolated from the culture of the marine-derived …

Design, synthesis and antimicrobial activity of heteroannulated chromeno[3′,2′:5,6]pyrido[2,3-d][1,3]thiazolo[3,2-a]pyrimidines

FM Alshareef, SA Al-Harbi, ES Allehyani… - Synthetic …, 2024 - Taylor & Francis
The current research is directed to construct a novel category of linear annulated chromeno
[3, 2: 5, 6] pyrido [2, 3-d][,] thiazolo [3, 2-a] pyrimidines. The chemical reactivity of the recently …

Dimeric 2-(2-phenethyl) chromones from agarwood of Aquilaria filaria

H Yang, P Wang, FZ Liu, JZ Yuan, CH Cai, F Wu… - Fitoterapia, 2023 - Elsevier
Abstract Four new 2-(2-phenethyl) chromone dimers (1–4) were isolated from EtOAc extract
of agarwood originating from Aquilaria filaria from Philippines. Their structures were …

Silver-catalysed three-component reactions of alkynyl aryl ketones, element selenium, and boronic acids leading to 3-organoselenylchromones

JR Lai, FD Yin, QS Guo, F Yuan, BF Nian… - Organic & …, 2022 - pubs.rsc.org
An Ag-catalysed three-component reaction of alkynyl aryl ketones bearing an ortho-methoxy
group, element selenium, and arylboronic acid, providing a facile route to …

Nucleophilic reactions with 3-formylchromones: A decade update

MA Ibrahim, M Abdel-Megid, O Farouk… - Synthetic …, 2024 - Taylor & Francis
The chemical reactivity of 3-formylchromones toward several carbon and nitrogen
nucleophiles is collected in this review. Certain annulated chromones and 3-heteroaryl …

First Synthesis of the Novel Triazolo[3,4-b][1,3,4]Thiadiazoles and Triazolo[3,4-b][1,3,4]Thiadiazines Linked Chromeno[2,3-b]Pyridine

MA Ibrahim, SA Al-Harbi, ES Allehyani… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Abstract The novel 3-(4-amino-5-thioxo-4, 5-dihydro-1 H-1, 2, 4-triazol-3-yl)-2 H-chromeno
[2, 3-b] pyridine-2, 5 (1 H)-dione (3) was efficiently synthesized from reaction of ethyl 2, 5 …

Novel heteroannulated chromeno[3′,2′:5,6]pyrido[2,3-d]pyrido[2′,3′: 4,5][1,3]thiazolo[3,2-a]pyrimidines: synthesis, characterization and antimicrobial evaluation

MA Ibrahim, SA Al-Harbi, ES Allehyani… - Polycyclic Aromatic …, 2024 - Taylor & Francis
The main aim of the current research is directed to find a suitable approach to construct a
new annulated systems namely chromeno [3′, 2′: 5, 6] pyrido [2, 3-d] pyrido [2′, 3′: 4 …

Two unprecedented 2-(2-phenethyl) chromone dimers from red soil agarwood of Aquilaria crassna

HX Chai, H Wang, J Zeng, WH Dong, WL Mei… - Phytochemistry …, 2024 - Elsevier
Abstract Two unprecedented 2-(2-phenethyl) chromone dimers, aquicrassones A and B (1
and 2), were isolated by HPLC-MS guided method from the ethanol extract of red soil …

Bi-2-(2-phenethyl) chromone derivatives from agarwood of Aquilaria filaria in the Philippines

HR Yang, H Wang, P Wang, FZ Liu, HX Chai, CH Cai… - Phytochemistry, 2024 - Elsevier
Abstract Twelve undescribed 2-(2-phenethyl) chromone dimers (1− 12) were isolated from
EtOAc extract of agarwood originating from Aquilaria filaria in the Philippines, guided by a …