[HTML][HTML] Advances and challenges in the treatment of esophageal cancer
S He, J Xu, X Liu, Y Zhen - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Esophageal cancer (EC) is one of the most common cancers with high morbidity and
mortality rates. EC includes two histological subtypes, namely esophageal squamous cell …
mortality rates. EC includes two histological subtypes, namely esophageal squamous cell …
The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
[HTML][HTML] Long non-coding RNA LINC00680 functions as a ceRNA to promote esophageal squamous cell carcinoma progression through the miR-423-5p/PAK6 axis
ST Xue, B Zheng, SQ Cao, JC Ding, GS Hu, W Liu… - Molecular cancer, 2022 - Springer
Background Esophageal squamous cell carcinoma (ESCC) is a common invasive
malignancy worldwide with poor clinical outcomes. Increasing amount of long non-coding …
malignancy worldwide with poor clinical outcomes. Increasing amount of long non-coding …
[HTML][HTML] microRNA-21-5p from M2 macrophage-derived extracellular vesicles promotes the differentiation and activity of pancreatic cancer stem cells by mediating …
J Chang, H Li, Z Zhu, P Mei, W Hu, X Xiong… - Cell Biology and …, 2021 - Springer
Aim Given the fact that tumor-associated macrophage-derived extracellular vesicles (EVs)
are attributable to tumor aggressiveness, this research intends to decode the mechanism of …
are attributable to tumor aggressiveness, this research intends to decode the mechanism of …
[HTML][HTML] Long noncoding RNA DGCR5 involves in tumorigenesis of esophageal squamous cell carcinoma via SRSF1-mediated alternative splicing of Mcl-1
Y Duan, Y Jia, J Wang, T Liu, Z Cheng, M Sang… - Cell death & …, 2021 - nature.com
Long noncoding RNAs (lncRNAs) emerge as essential roles in the regulation of alternative
splicing (AS) in various malignancies. Serine-and arginine-rich splicing factor 1 (SRSF1) …
splicing (AS) in various malignancies. Serine-and arginine-rich splicing factor 1 (SRSF1) …
PD-1/PD-L1 axis regulation in cancer therapy: The role of long non-coding RNAs and microRNAs
M Ashrafizadeh, A Zarrabi, K Hushmandi, V Zarrin… - Life sciences, 2020 - Elsevier
Cancer immunotherapy is a growing field nowadays. Among different molecular pathways,
PD-1/PD-L1 signaling pathway plays a significant role in the regulation of immune …
PD-1/PD-L1 signaling pathway plays a significant role in the regulation of immune …
Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis
C Wen, L Lin, R Zou, F Lin, Y Liu - Cell Cycle, 2022 - Taylor & Francis
Osteoarthritis is a degenerative joint disease and a leading cause of adult disability. Our
previous study has reported that mesenchymal stem cell-derived exosomes (MSC-Exo) …
previous study has reported that mesenchymal stem cell-derived exosomes (MSC-Exo) …
[HTML][HTML] Exosomes Mediate APP Dysregulation via APP-miR-185-5p Axis
L Ding, X Yang, X Xia, Y Li, Y Wang, C Li… - Frontiers in Cell and …, 2022 - frontiersin.org
APP misexpression plays a crucial role in triggering a complex pathological cascade,
leading to Alzheimer's disease (AD). But how the expression of APP is regulated in …
leading to Alzheimer's disease (AD). But how the expression of APP is regulated in …
[HTML][HTML] ORC6, a novel prognostic biomarker, correlates with T regulatory cell infiltration in prostate adenocarcinoma: a pan-cancer analysis
Y Lin, Y Zhang, Z Tuo, L Gao, D Ding, L Bi, D Yu, Z Lv… - BMC cancer, 2023 - Springer
Background The origin recognition complex (ORC), a six-subunit DNA-binding complex,
participates in DNA replication in cancer cells. Specifically in prostate cancers, ORC …
participates in DNA replication in cancer cells. Specifically in prostate cancers, ORC …
[HTML][HTML] Association of pericardiac adipose tissue with coronary artery disease
M Li, L Qi, Y Li, S Zhang, L Lin, L Zhou… - Frontiers in …, 2021 - frontiersin.org
Background and Aim Coronary artery disease (CAD) poses a worldwide health threat.
Compelling evidence shows that pericardial adipose tissue (PAT), a brown-like adipose …
Compelling evidence shows that pericardial adipose tissue (PAT), a brown-like adipose …