The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …

Chronic Kidney Disease in Agricultural Communities Numerous cases of chronic kidney
disease of unknown cause have emerged among agricultural workers and other manual …

Chronic kidney disease of uncertain etiology (CKDu) has emerged as a serious public
health concern in farming communities globally, especially in Sri Lanka with 5%–20% of the …

Results We identified 1607 articles, of which 26 met inclusion criteria. Eighteen (69%) were
conducted in known CKDu–endemic countries: Sri Lanka (38%), Nicaragua (19%), and El …

Increase in the prevalence of chronic kidney disease (CKD) is observed in Central America,
Sri Lanka and other tropical countries. It is named chronic interstitial nephritis in agricultural …

The current understanding of mammalian kidney development is largely based on mouse
models. Recent landmark studies revealed pervasive differences in renal embryogenesis …

The solute carrier (SLC) superfamily comprises more than 400 transport proteins mediating
the influx and efflux of substances such as ions, nucleotides, and sugars across biological …

Abstract Background Chronic Kidney Disease (CKD) of uncertain origin (CKDu) has affected
North Central Province (Anuradhapura and Polonnaruwa districts) of Sri Lanka. The cause …

Introduction: In the last two decades, chronic kidney disease of unknown etiology (CKDu)
has emerged as a significant contributor to the burden of chronic kidney disease (CKD) in …

There have been several global epidemics of chronic kidney disease of unknown etiology
(CKDu). Some, such as Itai-Itai disease in Japan and Balkan endemic nephropathy, have …