Endothelial cells play the most important role in construction of the blood–brain barrier.
Many studies have opted to use commercially available, easily transfected or immortalized …

The overwhelming increase in the global incidence of obesity and its associated
complications such as insulin resistance, atherosclerosis, pulmonary disease, and …

Abstract Treatment options for brain metastatic breast cancer are limited because the
molecular mechanism for how breast cancer cells infiltrate the brain is not fully understood …

Cerebral amyloid angiopathy (CAA) is a degenerative vasculopathy. We have previously
shown that transcription regulating proteins-inhibitor of DNA binding protein 3 (ID3) and the …

Background ID3 (inhibitor of DNA binding/differentiation-3) is a transcription factor that
enables metastasis by promoting stem cell-like properties in endothelial and tumor cells …

Abstract γδ T cells acquire their functional properties in the thymus, enabling them to exert
rapid innate‐like responses. To understand how distinct γδ T cell subsets are generated, we …

The rising global incidence of obesity cannot be fully explained within the context of
traditional risk factors such as an unhealthy diet, physical inactivity, aging, or genetics …

Background: Ischemic stroke (IS) is a fearful disease that can cause a variety of immune
events. Nevertheless, precise immune-related mechanisms have yet to be systematically …

The prognosis of patients with microvascular lesions remains poor because vascular
remodeling eventually obliterates the lumen. Here we have focused our efforts on vessel …

Polychlorinated biphenyls (PCBs) are persistent environmental pollutants that were banned
because of their potential carcinogenicity. Population studies have shown that PCBs are …