Chitosan-based nanomaterial as immune adjuvant and delivery carrier for vaccines

X Gong, Y Gao, J Shu, C Zhang, K Zhao - Vaccines, 2022 - mdpi.com
With the support of modern biotechnology, vaccine technology continues to iterate. The
safety and efficacy of vaccines are some of the most important areas of development in the …

How are natural-based polymers shaping the future of cancer immunotherapy—a review

DB Rodrigues, RL Reis, RP Pirraco - Polymer Reviews, 2024 - Taylor & Francis
With the increasing knowledge of cancer pathophysiology, new therapeutics based on the
modulation of the immune system have been developed, overcoming many of the …

Chitosan: modification and biodegradability of by-products

GI Edo, E Yousif, MH Al-Mashhadani - Polymer Bulletin, 2024 - Springer
Chitosan has so far been the only identified naturally occurring cationic polymer that is
alkaline of alkaline origin; it is derived from chitin. Along with having excellent biological …

A novel fluoropolymer as a protein delivery vector with robust adjuvant effect for cancer immunotherapy

YR Zhan, X He, ZY Huang, P Chen, MM Tian… - Journal of Materials …, 2023 - pubs.rsc.org
The inefficient treatment using protein-based nanovaccines is largely attributed to their
inadequate immunogenicity. Herein, we developed a novel fluoropolymer (PF) via ring …

[HTML][HTML] An infection-microenvironment-targeted and responsive peptide-drug nanosystem for sepsis emergency by suppressing infection and inflammation

W He, D Fu, Y Gai, X Liu, C Yang, Z Ye, X Chen… - Asian Journal of …, 2023 - Elsevier
Sepsis is a life-threatening emergency that causes millions of deaths every year due to
severe infection and inflammation. Nevertheless, current therapeutic regimens are …

Efficiency of chitosan nanocarriers in vaccinology for mucosal immunization

SC Gaglio, M Perduca, D Zipeto, G Bardi - Vaccines, 2023 - mdpi.com
The mucosal barrier constitutes a huge surface area, close to 40 m2 in humans, located
mostly in the respiratory, gastrointestinal and urogenital tracts and ocular cavities. It plays a …

The development of surface-modified liposomes as an intranasal delivery system for group a Streptococcus vaccines

J Yang, JC Boer, M Khongkow, S Phunpee, ZG Khalil… - Vaccines, 2023 - mdpi.com
Intranasal vaccine administration can overcome the disadvantages of injectable vaccines
and present greater efficiency for mass immunization. However, the development of …

The screening of α-glucosidase inhibitory peptides from β-conglycinin and hypoglycemic mechanism in HepG2 cells and zebrafish larvae

S Xue, L Yang, M Xu, Y Zhang, H Liu - International Journal of Biological …, 2024 - Elsevier
Inhibition of carbohydrate digestive enzymes is a key focus across diverse fields, given the
prominence of α-glucosidase inhibitors as preferred oral hypoglycaemic drugs for diabetes …

Microstructural, physico-chemical, antibacterial and antibiofilm efficacy of imipenem loaded chitosan nano-carrier systems to eradicate multidrug resistant …

IU Mufti, A Gondal, KM Kiyani, SM Mufti… - Materials Today …, 2023 - Elsevier
Acinetobacter baumannii, being labelled as “critical priority pathogen” is a major threat faced
by humanity nowadays as it is responsible for numerous life-threatening nosocomial …

Upconversion nanoparticles and their potential in the realm of biomedical sciences and theranostics

RS Ajee, PS Roy, S Dey, S Sundaresan - Journal of Nanoparticle …, 2024 - Springer
Interdisciplinary sciences have paved the way for the creation of new technologies that
could potentially alter how things were conventionally done. Biotechnology and …