[HTML][HTML] The role of T-cells in head and neck squamous cell carcinoma: from immunity to immunotherapy
MPS Damasio, CS Nascimento, LM Andrade… - Frontiers in …, 2022 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) encompass a group of complex entities
of tumours affecting the aerodigestive upper tract. The main risk factors are strongly related …
of tumours affecting the aerodigestive upper tract. The main risk factors are strongly related …
The mouse oral carcinoma (MOC) model: a 10-year retrospective on model development and head and neck cancer investigations
M Kono, S Saito, AM Egloff, CT Allen, R Uppaluri - Oral oncology, 2022 - Elsevier
Preclinical models of cancer have long been paramount to understanding tumor
development and advancing the treatment of cancer. Creating preclinical models that mimic …
development and advancing the treatment of cancer. Creating preclinical models that mimic …
[HTML][HTML] HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING
X Luo, CR Donnelly, W Gong, BR Heath… - The Journal of …, 2020 - Am Soc Clin Investig
The incidence of human papillomavirus–positive (HPV+) head and neck squamous cell
carcinoma (HNSCC) has surpassed that of cervical cancer and is projected to increase …
carcinoma (HNSCC) has surpassed that of cervical cancer and is projected to increase …
HPVTIMER: A shiny web application for tumor immune estimation in human papillomavirus‐associated cancers
The tumor immune microenvironment (TIME) is closely associated with tumor formation,
particularly linked to the human papillomavirus (HPV), and regulates tumor initiation …
particularly linked to the human papillomavirus (HPV), and regulates tumor initiation …
[HTML][HTML] The promise of Immuno-oncology: implications for defining the value of cancer treatment
HL Kaufman, MB Atkins, P Subedi, J Wu… - … for immunotherapy of …, 2019 - Springer
The rapid development of immuno-oncology (IO) therapies for multiple types of cancer has
transformed the cancer treatment landscape and brightened the long-term outlook for many …
transformed the cancer treatment landscape and brightened the long-term outlook for many …
[HTML][HTML] Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition
JM Newton, A Hanoteau, HC Liu, A Gaspero… - … for immunotherapy of …, 2019 - Springer
Abstract Background Immune checkpoint inhibitors (ICIs) for solid tumors, including those
targeting programmed cell death 1 (PD-1) and cytotoxic T lymphocyte-associated antigen 4 …
targeting programmed cell death 1 (PD-1) and cytotoxic T lymphocyte-associated antigen 4 …
Immunology‐guided biomaterial design for mucosal cancer vaccines
Cancer of mucosal tissues is a major cause of worldwide mortality for which only palliative
treatments are available for patients with late‐stage disease. Engineered cancer vaccines …
treatments are available for patients with late‐stage disease. Engineered cancer vaccines …
[HTML][HTML] The role of different immunocompetent cell populations in the pathogenesis of head and neck cancer—regulatory mechanisms of pro-and anti-cancer activity …
K Starska-Kowarska - Cancers, 2023 - mdpi.com
Simple Summary According to the latest GLOBOCAN data, head and neck squamous cell
carcinoma (HNSCC) represents the sixth most prevalent human malignancy. Recent studies …
carcinoma (HNSCC) represents the sixth most prevalent human malignancy. Recent studies …
[HTML][HTML] Up-regulation of hypoxia-inducible factor antisense as a novel approach to treat ovarian cancer
T Lu, J Tang, B Shrestha, BR Heath, L Hong, YL Lei… - Theranostics, 2020 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is estimated to kill~ 14,000 women in the United States in 2019.
Current chemotherapies to treat OC initially show therapeutic efficacy but frequently drug …
Current chemotherapies to treat OC initially show therapeutic efficacy but frequently drug …
Drug-mimicking nanofibrous peptide hydrogel for inhibition of inducible nitric oxide synthase
In this work, we develop a drug-mimicking nanofibrous peptide hydrogel that shows long-
term bioactivity comparable to a small-molecule inhibitor of inducible nitric oxide synthase …
term bioactivity comparable to a small-molecule inhibitor of inducible nitric oxide synthase …