Granzyme B (GzmB) is a serine protease emerging as an important mediator of skin injury,
inflammation and repair. Found at low levels in healthy skin, GzmB is dramatically elevated …

World Health Organization considered diabetes as one of the 20th century epidemics,
estimating that over 10% of the world population is diabetic or at high risk. Self-assessment …

Wound infection caused by Staphylococcus aureus (S. aureus) is a great challenge which
has caused significant burden and economic loss to the medical system. NZ2114, a …

Abstract Treatment for chronic diabetic foot ulcers is limited by the inability to simultaneously
address the excessive inflammation and impaired re-epithelization and remodeling …

Skin wound, a common form of skin damage in daily life, remains a serious challenge in
clinical treatment. Bioactive peptides with high efficiency have been considered as potential …

Granzyme B–expressing B cells have been shown to be an important regulatory B cell
subset in humans. However, it is unclear which subpopulations of B cells express GZMB …

Granzyme B (GZMB) was first identified as a factor that could eliminate cells such as tumour
cells and bacteria/virus‐infected cells. However, comprehensive studies conducted on …

Background/Aims: Antimicrobial peptides are effective promoters of wound healing but are
susceptible to degradation. In this study, we replaced the GIGDP unit on the N-terminal of …

Introduction: Granzyme B is a serine protease traditionally understood as having a role in
immune-mediated cytotoxicity. Over the past decade, this dogma has been challenged, with …

Abstract Background Granzyme K (GzmK) is a serine protease with minimal presence in
healthy tissues while abundant in inflamed tissues. Initially thought to play an exclusive role …