Axonal energy metabolism, and the effects in aging and neurodegenerative diseases

S Yang, JH Park, HC Lu - Molecular neurodegeneration, 2023 - Springer
Human studies consistently identify bioenergetic maladaptations in brains upon aging and
neurodegenerative disorders of aging (NDAs), such as Alzheimer's disease, Parkinson's …

Diffusion MRI tractography for neurosurgery: the basics, current state, technical reliability and challenges

JYM Yang, CH Yeh, C Poupon… - Physics in Medicine & …, 2021 - iopscience.iop.org
Diffusion magnetic resonance imaging (dMRI) tractography is currently the only imaging
technique that allows for non-invasive delineation and visualisation of white matter (WM) …

MR imaging of sca3/mjd

N Wan, Z Chen, L Wan, B Tang, H Jiang - Frontiers in neuroscience, 2020 - frontiersin.org
Spinocerebellar ataxia type 3/Machado–Joseph disease (SCA3/MJD) is a progressive
autosomal dominantly inherited cerebellar ataxia characterized by the aggregation of …

A critical review of connectome validation studies

T Sarwar, K Ramamohanarao… - NMR in Biomedicine, 2021 - Wiley Online Library
Diffusion MRI tractography is the most widely used macroscale method for mapping
connectomes in vivo. However, tractography is prone to various errors and biases, and thus …

Evaluation of early microstructural changes in the R6/1 mouse model of Huntington's disease by ultra-high field diffusion MR imaging

RG Gatto, C Weissmann, M Amin… - Neurobiology of …, 2021 - Elsevier
Diffusion MRI (dMRI) has been able to detect early structural changes related to
neurological symptoms present in Huntington's disease (HD). However, there is still a …

[HTML][HTML] Diffusion tractography of superior cerebellar peduncle and dentatorubrothalamic tracts in two autopsy confirmed progressive supranuclear palsy variants …

RG Gatto, PR Martin, F Ali, HM Clark, JR Duffy… - NeuroImage: Clinical, 2022 - Elsevier
Background Progressive supranuclear palsy (PSP) is a 4-repeat tauopathy with
neurodegeneration typically observed in the superior cerebellar peduncle (SCP) and …

Unveiling early cortical and subcortical neuronal degeneration in ALS mice by ultra-high field diffusion MRI

RG Gatto, M Amin, A Finkielsztein… - … Lateral Sclerosis and …, 2019 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease primarily characterized
by the progressive impairment of motor functions. However, a significant portion of affected …

Functional and structural brain alterations in encephalitis with LGI1 antibodies

J Qiao, X Zhao, S Wang, A Li, Z Wang, C Cao… - Frontiers in …, 2020 - frontiersin.org
Objective: The purpose of this study was to examine the neural substrates and mechanisms
that generate memory deficits, seizures and neuropsychiatric abnormalities in encephalitis …

Anesthetic modulation of water diffusion: Insights from a diffusion tensor imaging study

SL Peng, SM Huang, LWL Chu, SC Chiu - Medical Engineering & Physics, 2023 - Elsevier
Diffusion tensor imaging (DTI) in animal models are essential for translational neuroscience
studies. A critical step in animal studies is the use of anesthetics. Understanding the …

Diffusion tensor tractography characteristics of axonal injury in concussion/mild traumatic brain injury

SH Jang, YS Seo - Neural regeneration research, 2022 - journals.lww.com
The main advantage of diffusion tensor tractography is that it allows the entire neural tract to
be evaluated. In addition, configurational analysis of reconstructed neural tracts can indicate …