Surveying the Genetic Design Space for Transcription Factor-Based Metabolite Biosensors: Synthetic Gamma-Aminobutyric Acid and Propionate Biosensors in E. coli …
M Lebovich, LB Andrews - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Engineered probiotic bacteria have been proposed as a next-generation strategy for
noninvasively detecting biomarkers in the gastrointestinal tract and interrogating the gut …
noninvasively detecting biomarkers in the gastrointestinal tract and interrogating the gut …
Genetic Circuits for Feedback Control of Gamma-Aminobutyric Acid Biosynthesis in Probiotic Escherichia coli Nissle 1917
M Lebovich, MA Lora, J Gracia-David, LB Andrews - Metabolites, 2024 - mdpi.com
Engineered microorganisms such as the probiotic strain Escherichia coli Nissle 1917 (EcN)
offer a strategy to sense and modulate the concentration of metabolites or therapeutics in the …
offer a strategy to sense and modulate the concentration of metabolites or therapeutics in the …
Nucleic acid systems that enable bacteria to specifically target solid tumors via glucose-dependent viability
Y Jin - US Patent 12,042,517, 2024 - Google Patents
Provided is a nucleic acid system introduced into a bacterial strain to generate a genetically
engineered bacterial strain that grows in solid tumors but does not grow in non-tumor …
engineered bacterial strain that grows in solid tumors but does not grow in non-tumor …
Nucleic acid systems that enable bacteria to specifically target solid tumors via glucose-dependent viability
Y Jin - US Patent 11,458,172, 2022 - Google Patents
Provided is a nucleic acid system introduced into a bacterial strain to generate a genetically
engineered bacterial strain that grows in solid tumors but does not grow in non-tumor …
engineered bacterial strain that grows in solid tumors but does not grow in non-tumor …
Compositions and methods for modulating growth of a genetically modified gut bacterial cell
JL Sonnenburg, WR Whitaker, E Stanley… - US Patent …, 2022 - Google Patents
7,871,604 B1 7,981,651 B2 7,988,961 B2 8,486,389 B2 8,529,887 B2 8,759,039 B2
8,927,252 B2 9,011,834 B1 9,192,179 B2 9,371,510 B2 9,433,599 B2 9,487,764 B2 …
8,927,252 B2 9,011,834 B1 9,192,179 B2 9,371,510 B2 9,433,599 B2 9,487,764 B2 …
Bacteria for targeting tumors and treating cancer
Y Jin - US Patent 11,696,931, 2023 - Google Patents
US11696931B2 - Bacteria for targeting tumors and treating cancer - Google Patents
US11696931B2 - Bacteria for targeting tumors and treating cancer - Google Patents Bacteria for …
US11696931B2 - Bacteria for targeting tumors and treating cancer - Google Patents Bacteria for …
Compositions and methods for modulating growth of a genetically modified gut bacterial cell
JL Sonnenburg, WR Whitaker, E Stanley… - US Patent …, 2023 - Google Patents
2021-10-13 Assigned to THE BOARD OF TRUSTEES OF THE LELAND STANFORD
JUNIOR UNIVERSITY, NOVOME BIOTECHNOLOGIES, INC reassignment THE BOARD OF …
JUNIOR UNIVERSITY, NOVOME BIOTECHNOLOGIES, INC reassignment THE BOARD OF …